SCHEMBL4556987

SCHEMBL4556987

CS(=O)(=O)c1cc(C(F)(F)F)ccc1C=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 2/20 0.41
FEN1 P39748 2/20 0.41
DDR1 Q08345 1/20 0.39
MEN1 O00255 1/20 0.38
ALDH1A1 P00352 1/20 0.38
TSHR P16473 1/20 0.38
KMT2A Q03164 1/20 0.38
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
ADRA1A P35348 1/20 0.38
PDE2A O00408 1/20 0.38
KIF11 P52732 2/20 0.37
PTGS2 P35354 1/20 0.36
POLB P06746 2/20 0.36
MAPT P10636 1/20 0.36
ABCB11 O95342 1/20 0.36
GAA P10253 1/20 0.35
CNR2 P34972 1/20 0.35
LMNA P02545 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30487705 1.00 ALOX5AP (0.41) ALOX5APFEN1DDR1MEN1ALDH1A1
SCHEMBL6956211 0.83 POLB (0.39) MEN1ALDH1A1TSHRKMT2AATM
SCHEMBL28230701 0.80 ALOX5AP (0.46) ALOX5APFEN1DDR1MEN1ALDH1A1
SCHEMBL2798301 0.79 GAA (0.39) ALOX5APFEN1DDR1ALDH1A1KMT2A
SCHEMBL13233065 0.79 GAA (0.39) ALOX5APFEN1DDR1ALDH1A1KMT2A
SCHEMBL16495014 0.78 HSD11B1 (0.44) ALDH1A1TSHRMAPTCNR2LMNA
SCHEMBL23841300 0.77 CES2 (0.47) ALOX5APFEN1DDR1MEN1ALDH1A1
SCHEMBL12335461 0.77 ALOX5AP (0.50) ALOX5APFEN1MEN1ALDH1A1TSHR
SCHEMBL6076943 0.77 KDM4E (0.41) ALOX5APFEN1ALDH1A1ADRA1APTGS2
SCHEMBL16021159 0.77 MCL1 (0.47) ALOX5APFEN1MEN1ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109516956-B 5-pyrazole ketone compound and application thereof 湖南新长山农业发展股份有限公司 2020-09-15 CN claimed
CN-114585731-B Mutant hydroxyphenylpyruvate dioxygenase polypeptide, encoding gene and application thereof 北京大北农生物技术有限公司 2024-07-12 CN disclosed
CN-114854702-B Herbicide tolerance protein, coding gene and application thereof 北京大北农生物技术有限公司 2024-04-19 CN disclosed
CN-114854702-A Herbicide tolerance protein, coding gene and application thereof 北京大北农生物技术有限公司 2022-08-05 CN disclosed
CN-111304178-B Herbicide tolerance protein, coding gene and application thereof 北京大北农生物技术有限公司 2022-06-03 CN disclosed
CN-111334484-B Herbicide tolerance protein, coding gene and application thereof 北京大北农生物技术有限公司 2022-06-03 CN disclosed
CN-114585731-A Mutant hydroxyphenylpyruvate dioxygenase polypeptide, coding gene and application thereof 北京大北农生物技术有限公司 2022-06-03 CN disclosed
CN-110628732-B Herbicide tolerance protein, coding gene and application thereof 北京大北农生物技术有限公司 2022-04-15 CN disclosed
CN-113574173-A Mutant hydroxyphenylpyruvate dioxygenase polypeptide, coding gene and application thereof 北京大北农生物技术有限公司 2021-10-29 CN disclosed
CN-110656094-B Herbicide tolerance protein, coding gene and application thereof 北京大北农生物技术有限公司 2021-07-30 CN disclosed
WO-2014154829-A1 HERBICIDAL COMPOUNDS SYNGENTA LIMITED (GB) 2014-10-02 WO disclosed
CN-103999864-A Herbicide combination comprising dimethoxytriazinyl-substituted difluoromethanesulfonylanilides BAYER CROPSCIENCE AG 2014-08-27 CN disclosed
CN-103981149-A Methods and means to modify a plant genome BAYER CROPSCIENCE NV 2014-08-13 CN disclosed
CN-103890181-A Methods and means for modifying plant genomes BAYER CROPSCIENCE NV 2014-06-25 CN disclosed
CN-102186349-B Herbicidal combination containing dimethoxytriazinyl-substituted difluoromethane sulfonylanilides BAYER CROPSCIENCE AG 2014-05-28 CN disclosed
CN-102613207-A Synergistic weeding compound GUANGDONG ZHONGXUN AGRI TECH 2012-08-01 CN disclosed
CN-102186349-A Herbicidal combination containing dimethoxytriazinyl-substituted difluoromethane sulfonylanilides BAYER CROPSCIENCE AG 2011-09-14 CN disclosed
WO-2009144079-A1 NEW MUTATED HYDROXYPHENYLPYRUVATE DIOXYGENASE, DNA SEQUENCE AND ISOLATION OF PLANTS WHICH ARE TOLERANT TO HPPD INHIBITOR HERBICIDES BAYER BIOSCIENCE N.V. (BE) 2009-12-03 WO disclosed
CN-1312680-A Herbicidal compositions containing acylated aminophenylsulfonylureas AVENTIES CROP SCIENCES GMBH (DE) 2001-09-12 CN disclosed
WO-1999024409-A1 ISOXAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES NOVARTIS AG (CH) 1999-05-20 WO disclosed