Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.59 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | CDK1 | P06493 | 2/20 | 0.51 |
| ▸ | IGF1R | P08069 | 2/20 | 0.51 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.51 |
| ▸ | BRAF | P15056 | 2/20 | 0.51 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.51 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.51 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.51 |
| ▸ | JAK1 | P23458 | 2/20 | 0.51 |
| ▸ | CDK2 | P24941 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8709483 | 0.88 | HSD11B1 (0.51) | SLC6A7DCTPP1ALDH1A1MAPK1KDM4E | |
| SCHEMBL9038228 | 0.85 | CDK5 (0.48) | SLC6A7DCTPP1ALDH1A1HPGDCDK5 | |
| SCHEMBL8709493 | 0.84 | ALDH1A1 (0.48) | SLC6A7ALDH1A1DRD2DRD3KDM4E | |
| SCHEMBL7868110 | 0.82 | PARP1 (0.47) | SLC6A7KMT2AALDH1A1SMN1; SMN2MAPK1 | |
| Atevirdine Mesylate SCHEMBL29365699 | 0.81 | HRH4 (0.57) | MEN1KMT2ADRD2DRD3 | |
| SCHEMBL10281154 | 0.81 | DRD2 (0.49) | SLC6A7DCTPP1MEN1KMT2AALDH1A1 | |
| Atevirdine Mesylate SCHEMBL29377031 | 0.81 | HRH4 (0.57) | MEN1KMT2ADRD2DRD3 | |
| Atevirdine Mesylate SCHEMBL356038 | 0.81 | HRH4 (0.57) | MEN1KMT2ADRD2DRD3 | |
| SCHEMBL8985854 | 0.80 | ALDH1A1 (0.49) | MEN1KMT2AALDH1A1GAAHPGD | |
| SCHEMBL8713892 | 0.80 | PARP1 (0.44) | SLC6A7DCTPP1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0507861-A1 | DIAROMATIC SUBSTITUTED ANTI-AIDS COMPOUNDS. | UPJOHN CO (US) | 1992-10-14 | — | — | EP | disclosed |
| WO-1991009849-A1 | DIAROMATIC SUBSTITUTED ANTI-AIDS COMPOUNDS | THE UPJOHN COMPANY (US) | 1991-07-11 | — | — | WO | disclosed |