Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 7/20 | 0.43 |
| ▸ | CA2 | P00918 | 7/20 | 0.43 |
| ▸ | CA9 | Q16790 | 7/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9690121 | 1.00 | CA12 (0.43) | CA12CA2CA9MAPTSMN1; SMN2 | |
| SCHEMBL9690036 | 0.83 | SMN1; SMN2 (0.39) | CA12CA2CA9MAPTSMN1; SMN2 | |
| SCHEMBL9690033 | 0.83 | SMN1; SMN2 (0.39) | CA12CA2CA9MAPTSMN1; SMN2 | |
| SCHEMBL9690004 | 0.76 | SARM1 (0.40) | MAPTSMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL9690756 | 0.76 | KMT2A (0.34) | MAPTSMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL9690760 | 0.76 | KMT2A (0.34) | MAPTSMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL9690550 | 0.75 | SIGMAR1 (0.36) | MAPTSMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL9690757 | 0.75 | MAPT (0.49) | MAPTSMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL9690554 | 0.75 | SIGMAR1 (0.36) | MAPTSMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL9690750 | 0.75 | MAPT (0.49) | MAPTSMN1; SMN2MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520275-A2 | 2-(3-Substituted phenylhydrazino)-2-thiazoline and 2-(3-substituted phenylazo)-2-thiazoline, their preparation and their use against ectoparasites | BAYER AG (DE) | 1992-12-30 | — | — | EP | disclosed |