Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 10/20 | 0.54 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11788673 | 0.82 | ITGB3 (0.50) | FFAR1EPHX2NR1H4ITGB3ITGA2B | |
| SCHEMBL3672272 | 0.81 | CYP2C9 (0.48) | CA1CA2ST14 | |
| SCHEMBL7303517 | 0.80 | NR1H4 (0.61) | FFAR1FFAR4EPHX2NR1H4ITGB3 | |
| Trifluoroacetic Acid SCHEMBL28211908 | 0.80 | TMPRSS6 (0.47) | FFAR1ITGB3ITGA2BST14 | |
| SCHEMBL4109710 | 0.79 | FFAR1 (0.53) | FFAR1FFAR4EPHX2NR1H4ITGB3 | |
| Hydrochloric Acid SCHEMBL9264373 | 0.79 | NR1H4 (0.60) | FFAR1FFAR4EPHX2NR1H4ITGB3 | |
| SCHEMBL1916981 | 0.79 | KMT2A (0.62) | FFAR1FFAR4EPHX2NR1H4PPARG | |
| SCHEMBL4104833 | 0.79 | KMT2A (0.62) | EPHX2NR1H4ST14 | |
| Bicarbonate SCHEMBL27358699 | 0.78 | CYP2D6 (0.56) | CA1CA2 | |
| SCHEMBL27357156 | 0.78 | CA2 (0.45) | CA1CA2ST14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0181592-B1 | USE OF SPERGUALIN DERIVATIVES FOR THE PREPARATION OF MEDICAMENTS HAVING IMMUNOSUPPRESSIVE ACTIVITY | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 1992-09-16 | — | — | EP | disclosed |
| US-4851446-A | SPERGUALIN-LIKE GUANIDINES | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1989-07-25 | — | — | US | disclosed |
| EP-0181592-A2 | Use of spergualin derivatives for the preparation of medicaments having immunosuppressive activity | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 1986-05-21 | — | — | EP | disclosed |