Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 6/20 | 0.36 |
| ▸ | PPARA | Q07869 | 5/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | CASR | P41180 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9690648 | 0.80 | NPSR1 (0.38) | NPSR1MAPTPPARGPPARAALOX5 | |
| SCHEMBL9689951 | 0.65 | TDP1 (0.41) | MAPTPPARA | |
| SCHEMBL9688569 | 0.63 | KDM4E (0.43) | MAPTTP53POLB | |
| SCHEMBL9689433 | 0.63 | ALDH1A1 (0.49) | MAPTTP53POLB | |
| SCHEMBL15088758 | 0.62 | AKR1C3 (0.78) | MTNR1A | |
| SCHEMBL9584965 | 0.62 | AKR1C3 (0.78) | MTNR1A | |
| SCHEMBL6836190 | 0.61 | TP53 (0.71) | TP53 | |
| SCHEMBL347957 | 0.61 | CA12 (0.54) | MTNR1A | |
| SCHEMBL10644244 | 0.60 | THRA (0.49) | PPARGPPARATP53 | |
| SCHEMBL9591536 | 0.60 | AKR1C3 (0.74) | MTNR1APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0506011-A1 | Tetrazoleacetic acid derivatives having aldose reductase inhibitory activity | Wakamoto Pharmaceutical Co., Ltd. (JP) | 1992-09-30 | — | — | EP | disclosed |