Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 3/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CDC42 | P60953 | 1/20 | 0.39 |
| ▸ | RAC1 | P63000 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | SCD | O00767 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9690025 | 0.91 | PPARA (0.42) | TDP1PPARAPTGS2AKR1C3AKR1C2 | |
| SCHEMBL9690648 | 0.87 | NPSR1 (0.38) | PPARATSHRMAPTSCD | |
| SCHEMBL9688900 | 0.83 | KDM4E (0.41) | PTGS2PTGS1CYP1A2RAB9AKDM4E | |
| SCHEMBL9689963 | 0.77 | HDAC3 (0.43) | NPC1RAB9AKDM4EMAPTCA2 | |
| SCHEMBL9689940 | 0.77 | TDP1 (0.40) | TDP1PPARAPTGS2AKR1C3AKR1C2 | |
| SCHEMBL9689398 | 0.72 | TDP1 (0.41) | TDP1PTGS2AKR1C3AKR1C2PTGS1 | |
| SCHEMBL9689396 | 0.71 | KDM4E (0.49) | TDP1KDM4EMAPTCA2MEN1 | |
| SCHEMBL3554931 | 0.69 | KDM4E (0.56) | TSHRNPC1RAB9AKDM4EMAPT | |
| SCHEMBL9688521 | 0.68 | SIGMAR1 (0.38) | TDP1CYP1A2RAB9AKDM4EMAPT | |
| SCHEMBL12871087 | 0.66 | HDAC6 (0.56) | CYP1A2TSHRNPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0506011-A1 | Tetrazoleacetic acid derivatives having aldose reductase inhibitory activity | Wakamoto Pharmaceutical Co., Ltd. (JP) | 1992-09-30 | — | — | EP | disclosed |