Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | PRNP | P04156 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | USP5 | P45974 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | GRM6 | O15303 | 1/20 | 0.31 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9689439 | 0.88 | KDM4E (0.45) | KDM4EALDH1A1PRNPHPGDRAB9A | |
| SCHEMBL9688573 | 0.83 | ALDH1A1 (0.47) | KDM4EALDH1A1PRNPHPGDRAB9A | |
| SCHEMBL9689433 | 0.81 | ALDH1A1 (0.49) | KDM4EALDH1A1PRNPHPGDRAB9A | |
| SCHEMBL9688895 | 0.78 | KDM4E (0.43) | KDM4EALDH1A1PRNPHPGDRAB9A | |
| SCHEMBL8947138 | 0.76 | KMT2A (0.49) | KDM4EALDH1A1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL9689975 | 0.74 | GPR139 (0.37) | KDM4EALDH1A1PRNPHPGDRAB9A | |
| SCHEMBL9469693 | 0.73 | KDM4E (0.46) | KDM4EALDH1A1PRNPHPGDRAB9A | |
| SCHEMBL9689989 | 0.73 | APP (0.45) | KDM4EALDH1A1PRNPHPGDRAB9A | |
| SCHEMBL9690579 | 0.72 | KDM4E (0.45) | KDM4EALDH1A1PRNPHPGDRAB9A | |
| SCHEMBL9688900 | 0.71 | KDM4E (0.41) | KDM4EALDH1A1PRNPHPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0506011-A1 | Tetrazoleacetic acid derivatives having aldose reductase inhibitory activity | Wakamoto Pharmaceutical Co., Ltd. (JP) | 1992-09-30 | — | — | EP | disclosed |