Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6331583 | 0.82 | MAPT (0.46) | MAPTHSD17B10NPC1RAB9ATP53 | |
| SCHEMBL9690700 | 0.78 | ALDH1A1 (0.39) | MAPTRAB9ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL9690716 | 0.78 | ALDH1A1 (0.39) | MAPTNPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL9581166 | 0.78 | ALDH1A1 (0.39) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9690773 | 0.77 | GRIN2D (0.37) | MAPTHSD17B10SMN1; SMN2ALDH1A1 | |
| SCHEMBL11747051 | 0.76 | ALDH1A1 (0.53) | MAPTHSD17B10NPC1RAB9ATP53 | |
| SCHEMBL9690768 | 0.75 | ALDH1A1 (0.50) | MAPTSMN1; SMN2GAAALDH1A1KMT2A | |
| SCHEMBL9689448 | 0.75 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL9689432 | 0.74 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL9689560 | 0.74 | ALDH1A1 (0.36) | NPC1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520275-A2 | 2-(3-Substituted phenylhydrazino)-2-thiazoline and 2-(3-substituted phenylazo)-2-thiazoline, their preparation and their use against ectoparasites | BAYER AG (DE) | 1992-12-30 | — | — | EP | disclosed |