Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 2/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.42 |
| ▸ | EDNRB | P24530 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 6/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9536684 | 0.81 | MAPK8 (0.55) | MAPK8PPARGHDAC1HDAC8HDAC6 | |
| SCHEMBL9535760 | 0.76 | AGTR1 (0.47) | MAPK8PPARGPLA2G2A | |
| SCHEMBL9531841 | 0.74 | PPARG (0.52) | MAPK8PPARGPLA2G2A | |
| SCHEMBL9531904 | 0.71 | PPARG (0.50) | EDNRBPPARGPLA2G2A | |
| SCHEMBL9534507 | 0.70 | PPARG (0.53) | PPARGPLA2G2A | |
| SCHEMBL9531316 | 0.68 | AGTR1 (0.54) | PPARG | |
| SCHEMBL29264863 | 0.68 | SLC6A4 (0.45) | MAPK8PPARG | |
| SCHEMBL6276231 | 0.67 | SLC6A3 (0.71) | HDAC8 | |
| SCHEMBL7098029 | 0.66 | PPARG (0.64) | PPARG | |
| SCHEMBL9531279 | 0.66 | AGTR1 (0.55) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0500297-A1 | Substituted pyridinones and pyrimidinones as angiotensin II antagonists | FISONS plc (GB) | 1992-08-26 | — | — | EP | disclosed |