Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.57 |
| ▸ | EGFR | P00533 | 2/20 | 0.57 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.57 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | BLM | P54132 | 3/20 | 0.54 |
| ▸ | NSD2 | O96028 | 2/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.50 |
| ▸ | TERT | O14746 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29374910 | 0.87 | TOP2B (0.70) | MAPTMAPK1L3MBTL1RAB9ASMN1; SMN2 | |
| SCHEMBL23404 | 0.87 | TOP2B (0.70) | MAPTMAPK1L3MBTL1RAB9ASMN1; SMN2 | |
| SCHEMBL29670831 | 0.87 | TOP2B (0.70) | MAPTMAPK1L3MBTL1RAB9ASMN1; SMN2 | |
| SCHEMBL55230 | 0.86 | MAPT (0.74) | MAPTMAPK1L3MBTL1RAB9ASMN1; SMN2 | |
| SCHEMBL29358770 | 0.86 | MAPT (0.74) | MAPTMAPK1L3MBTL1RAB9ASMN1; SMN2 | |
| SCHEMBL29419222 | 0.86 | MAPT (0.74) | MAPTMAPK1L3MBTL1RAB9ASMN1; SMN2 | |
| SCHEMBL21300705 | 0.85 | MAPT (0.59) | MAPTMAPK1L3MBTL1RAB9ASMN1; SMN2 | |
| SCHEMBL20710632 | 0.84 | TOP2B (0.62) | MAPTMAPK1L3MBTL1RAB9ASMN1; SMN2 | |
| SCHEMBL8947726 | 0.83 | TOP2B (0.74) | MAPTMAPK1L3MBTL1RAB9ASMN1; SMN2 | |
| SCHEMBL20333928 | 0.83 | MAPT (0.50) | MAPTMAPK1L3MBTL1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112359-A | Diaminoanthraquinone dyes for hair dyes with carriers and water | CLAIROL, INC. (US) | 1992-05-12 | — | — | US | claimed |