Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9690728 | 0.78 | RXFP1 (0.46) | NOTUMALDH1A1TSHRMAPK1GAA | |
| SCHEMBL9689145 | 0.73 | TP53 (0.35) | NOTUMALDH1A1LMNATSHRGAA | |
| SCHEMBL27360285 | 0.67 | GABRA1 (0.38) | GAAMAPTGABRA1GABRG2GABRB3 | |
| SCHEMBL25451410 | 0.67 | S1PR1 (0.42) | DGAT1NOTUMS1PR1S1PR5SIGMAR1 | |
| SCHEMBL14937607 | 0.66 | CYP1A2 (0.45) | DGAT1NOTUMS1PR1SIGMAR1KCNH2 | |
| SCHEMBL59138 | 0.66 | NOTUM (0.55) | DGAT1NOTUMS1PR1S1PR5HTT | |
| SCHEMBL18117721 | 0.65 | MAPT (0.54) | NOTUMS1PR1S1PR5SIGMAR1HTT | |
| SCHEMBL27351163 | 0.65 | CYP17A1 (0.34) | HTTLMNATSHRMAPT | |
| SCHEMBL2368381 | 0.65 | RXFP1 (0.44) | NOTUMS1PR1S1PR5SIGMAR1KMT2A | |
| SCHEMBL17818434 | 0.64 | CCR1 (0.48) | DGAT1NOTUMS1PR1S1PR5SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483027-A2 | Triazolopyridazines, methods for their preparation, their use as herbicides and intermediates | RHONE-POULENC AGROCHIMIE (FR) | 1992-04-29 | — | — | EP | disclosed |