Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1664963 | 0.80 | SMN1; SMN2 (0.50) | NPC1RAB9AMAPTLMNASMN1; SMN2 | |
| SCHEMBL9690979 | 0.75 | MAPT (0.43) | TP53HSD11B1NPC1RAB9AMAPT | |
| SCHEMBL9691174 | 0.73 | CYP17A1 (0.49) | TP53NPC1RAB9AMAPTLMNA | |
| SCHEMBL9690785 | 0.73 | DGAT1 (0.46) | MAPTLMNAALDH1A1GAATSHR | |
| SCHEMBL24121997 | 0.70 | RXFP1 (0.38) | LMNASMN1; SMN2RXFP1TSHR | |
| SCHEMBL9691041 | 0.67 | RAB9A (0.36) | TP53HSD11B1NPC1RAB9AMAPT | |
| SCHEMBL9690712 | 0.66 | MAPT (0.43) | NPC1RAB9AMAPTLMNASMN1; SMN2 | |
| Bromide SCHEMBL16494617 | 0.66 | NOS3 (0.32) | — | |
| SCHEMBL9689135 | 0.66 | CYP17A1 (0.48) | NPC1RAB9ALMNANFKB1NFKB2 | |
| SCHEMBL6619651 | 0.65 | RXFP1 (0.34) | MAPTLMNASMN1; SMN2ALDH1A1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483027-A2 | Triazolopyridazines, methods for their preparation, their use as herbicides and intermediates | RHONE-POULENC AGROCHIMIE (FR) | 1992-04-29 | — | — | EP | disclosed |