Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.36 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | XIAP | P98170 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9666877 | 0.90 | SMN1; SMN2 (0.39) | RAB9ANPC1SMN1; SMN2ALOX15ABCC8 | |
| SCHEMBL9692016 | 0.84 | RAB9A (0.37) | RAB9ANPC1SMN1; SMN2ALOX15KDR | |
| SCHEMBL9691327 | 0.81 | MAPT (0.39) | RAB9ANPC1SMN1; SMN2ABCC8KCNJ11 | |
| SCHEMBL9689720 | 0.80 | PTPN11 (0.39) | RAB9ANPC1SMN1; SMN2ABCC8KCNJ11 | |
| SCHEMBL9581101 | 0.79 | RAB9A (0.37) | RAB9ANPC1SMN1; SMN2ABCC8KCNJ11 | |
| SCHEMBL9691348 | 0.78 | ABCC8 (0.37) | RAB9ANPC1SMN1; SMN2ABCC8KCNJ11 | |
| SCHEMBL9691875 | 0.78 | XIAP (0.39) | RAB9ANPC1SMN1; SMN2ABCC8KCNJ11 | |
| SCHEMBL9668730 | 0.78 | KDR (0.39) | RAB9ANPC1SMN1; SMN2ALOX15KDR | |
| SCHEMBL8965922 | 0.74 | TRPA1 (0.37) | RAB9ANPC1SMN1; SMN2POLBALDH1A1 | |
| SCHEMBL8639304 | 0.72 | KDM4E (0.47) | SMN1; SMN2ALOX15ALDH1A1KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0508901-A2 | Alpha-methylene-4-[(phenoxy)methyl)]5-thiazolacetic acid derivatives, process for their preparation, intermediates in this process, their use as fungicides and compositions containing them | ROUSSEL UCLAF (FR) | 1992-10-14 | — | — | EP | claimed |
| EP-0508901-A2 | Alpha-methylene-4-[(phenoxy)methyl)]5-thiazolacetic acid derivatives, process for their preparation, intermediates in this process, their use as fungicides and compositions containing them | ROUSSEL UCLAF (FR) | 1992-10-14 | — | — | EP | disclosed |