Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.46 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.46 |
| ▸ | SCN1A | P35498 | 2/20 | 0.46 |
| ▸ | HTR2B | P41595 | 2/20 | 0.46 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.46 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11009533 | 0.87 | MAPT (0.60) | KMT2AMAPTALDH1A1KDM4EADORA3 | |
| SCHEMBL11111322 | 0.83 | ALDH1A1 (0.51) | KMT2AMAPTALDH1A1KDM4EADORA3 | |
| SCHEMBL6427770 | 0.78 | ADORA3 (0.67) | KMT2AMAPTALDH1A1KDM4EADORA3 | |
| SCHEMBL10369519 | 0.76 | ADORA3 (0.58) | KMT2AMAPTALDH1A1KDM4EADORA3 | |
| SCHEMBL11116098 | 0.76 | KMT2A (0.44) | KMT2AMAPTALDH1A1KDM4EADORA3 | |
| SCHEMBL9838777 | 0.75 | ALDH1A1 (0.52) | KMT2AMAPTALDH1A1KDM4EADORA3 | |
| SCHEMBL9689499 | 0.75 | ADORA3 (0.62) | KMT2AMAPTALDH1A1KDM4EADORA3 | |
| SCHEMBL11360822 | 0.75 | ADORA3 (0.62) | KMT2AMAPTALDH1A1KDM4EADORA3 | |
| SCHEMBL11114191 | 0.74 | CACNA1C (0.53) | KMT2AMAPTALDH1A1KDM4EADORA3 | |
| SCHEMBL6425245 | 0.74 | CACNA1D (0.61) | KMT2AMAPTALDH1A1KDM4EADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0071819-B2 | DIHYDROPYRIDINES WITH A POSITIVE INOTROPIC ACTIVITY, THEIR USE IN PHARMACEUTICAL PREPARATIONS, AND PROCESSES FOR THEIR PREPARATION | BAYER AG (DE) | 1992-06-10 | — | — | EP | disclosed |
| EP-0071819-B1 | DIHYDROPYRIDINES WITH A POSITIVE INOTROPIC ACTIVITY, THEIR USE IN PHARMACEUTICAL PREPARATIONS, AND PROCESSES FOR THEIR PREPARATION | BAYER AG (DE) | 1987-04-22 | — | — | EP | disclosed |