SCHEMBL9691985

SCHEMBL9691985

COC(=O)CCNCCC1Cc2ccccc2OC1(C)C

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.37
MALT1 Q9UDY8 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
NOTUM Q6P988 1/20 0.34
MTNR1A P48039 2/20 0.33
MTNR1B P49286 2/20 0.33
CNR1 P21554 1/20 0.33
CNR2 P34972 1/20 0.33
TP53 P04637 1/20 0.33
CA12 O43570 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
CA14 Q9ULX7 1/20 0.33
KDM4E B2RXH2 1/20 0.32
MITF O75030 1/20 0.32
LMNA P02545 1/20 0.32
POLB P06746 1/20 0.32
MAPK1 P28482 1/20 0.32
HTT P42858 1/20 0.32
HIF1A Q16665 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9692609 0.99 LTA4H (0.37) LTA4HMALT1SMN1; SMN2NOTUMMTNR1A
SCHEMBL9692382 0.90 SMN1; SMN2 (0.37) LTA4HMALT1SMN1; SMN2NOTUMCNR1
SCHEMBL9691921 0.88 HTT (0.35) LTA4HSMN1; SMN2MTNR1AMTNR1BKDM4E
SCHEMBL10512171 0.87 MTNR1A (0.34) SMN1; SMN2MTNR1AMTNR1BTP53KDM4E
Hydrochloric Acid SCHEMBL9692716 0.86 MTNR1A (0.33) SMN1; SMN2MTNR1AMTNR1BTP53KDM4E
SCHEMBL9692329 0.85 SMN1; SMN2 (0.38) MALT1SMN1; SMN2MTNR1ACA12CA7
Hydrochloric Acid SCHEMBL9692351 0.84 SMN1; SMN2 (0.38) MALT1SMN1; SMN2MTNR1ACA12CA7
SCHEMBL9692884 0.83 MEN1 (0.35) LTA4HMALT1SMN1; SMN2NOTUMCNR1
SCHEMBL9692305 0.82 ABCB1 (0.43) MALT1KDM4E
SCHEMBL9692870 0.81 SMN1; SMN2 (0.36) MALT1SMN1; SMN2NOTUMCNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0322361-A2 Hydrogenated 1-benzooxacycloalkyl pyridine-carboxylic-acid compounds CIBA-GEIGY AG (CH) 1989-06-28 EP claimed
US-5112855-A Nootropic Agents CIBA-GEIGY CORPORATION (US) 1992-05-12 US disclosed
US-4957928-A NOOTROPIC AGENTS, COGNITION ACTIVATORS CIBA-GEIGY CORPORATION (US) 1990-09-18 US disclosed
EP-0322361-A2 Hydrogenated 1-benzooxacycloalkyl pyridine-carboxylic-acid compounds CIBA-GEIGY AG (CH) 1989-06-28 EP disclosed