Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9691985 | 0.90 | LTA4H (0.37) | SMN1; SMN2KDM4EMITFLMNAPOLB | |
| Hydrochloric Acid SCHEMBL9692609 | 0.89 | LTA4H (0.37) | SMN1; SMN2KDM4EMITFLMNAPOLB | |
| SCHEMBL9692870 | 0.82 | SMN1; SMN2 (0.36) | SMN1; SMN2MALT1NOTUMCNR1CNR2 | |
| SCHEMBL9692884 | 0.80 | MEN1 (0.35) | SMN1; SMN2KDM4EMITFLMNAPOLB | |
| SCHEMBL9691921 | 0.78 | HTT (0.35) | SMN1; SMN2KDM4EMITFLMNAPOLB | |
| SCHEMBL9692800 | 0.77 | MALT1 (0.53) | MALT1TP53 | |
| SCHEMBL10512171 | 0.77 | MTNR1A (0.34) | SMN1; SMN2KDM4EMITFLMNAPOLB | |
| Hydrochloric Acid SCHEMBL9692716 | 0.76 | MTNR1A (0.33) | SMN1; SMN2KDM4EMITFLMNAPOLB | |
| SCHEMBL9692745 | 0.76 | SIGMAR1 (0.42) | SMN1; SMN2KDM4ELMNAPOLB | |
| SCHEMBL9692329 | 0.75 | SMN1; SMN2 (0.38) | SMN1; SMN2MALT1CA12CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0322361-A2 | Hydrogenated 1-benzooxacycloalkyl pyridine-carboxylic-acid compounds | CIBA-GEIGY AG (CH) | 1989-06-28 | — | — | EP | claimed |
| US-5112855-A | Nootropic Agents | CIBA-GEIGY CORPORATION (US) | 1992-05-12 | — | — | US | disclosed |
| US-4957928-A | NOOTROPIC AGENTS, COGNITION ACTIVATORS | CIBA-GEIGY CORPORATION (US) | 1990-09-18 | — | — | US | disclosed |
| EP-0322361-A2 | Hydrogenated 1-benzooxacycloalkyl pyridine-carboxylic-acid compounds | CIBA-GEIGY AG (CH) | 1989-06-28 | — | — | EP | disclosed |