Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9692311 | 0.95 | SLC6A3 (0.37) | SLC6A3SLC6A4HCAR3HCAR2HTT | |
| SCHEMBL9691988 | 0.85 | TDP1 (0.39) | SLC6A3SLC6A4HTTALDH1A1MAPT | |
| SCHEMBL9691713 | 0.85 | SLC6A3 (0.38) | SLC6A3SLC6A4HTTALDH1A1MAPT | |
| SCHEMBL9692259 | 0.84 | ATM (0.50) | ALDH1A1ATML3MBTL1POLBSMN1; SMN2 | |
| SCHEMBL11479516 | 0.84 | SLC6A4 (0.37) | SLC6A3SLC6A4HTTALDH1A1MAPT | |
| SCHEMBL8115242 | 0.83 | HTT (0.53) | HTTALDH1A1MAPTITGA4ATM | |
| SCHEMBL9692296 | 0.83 | RAB9A (0.46) | ALDH1A1MAPTATML3MBTL1SMN1; SMN2 | |
| SCHEMBL9692693 | 0.81 | RAB9A (0.38) | SLC6A3HTTALDH1A1MAPTITGA4 | |
| SCHEMBL9690185 | 0.81 | SLC6A2 (0.42) | HTTALDH1A1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL9692252 | 0.81 | ALDH1A1 (0.45) | HTTALDH1A1MAPTITGA4ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0153692-B1 | METHOD FOR ISOMERIZATION A GLYCIDATE DERIVATIVE | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1992-07-29 | — | — | EP | disclosed |
| US-4621150-A | METAL PERHALATE OR SULFONATE OR COMPLEX; GLYCIDATE, 2-HYDROXY-3-BUTENOATE, EPOXIDE | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1986-11-04 | — | — | US | disclosed |
| EP-0153692-A2 | Method for isomerization a glycidate derivative | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1985-09-04 | — | — | EP | disclosed |