Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.36 |
| ▸ | KCNE1 | P15382 | 3/20 | 0.35 |
| ▸ | KCNQ1 | P51787 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 4/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9692319 | 0.85 | LMNA (0.36) | CA12CA1CA9SMN1; SMN2 | |
| SCHEMBL10517728 | 0.82 | KCNE1 (0.34) | KCNE1KCNQ1HIF1AESR1 | |
| SCHEMBL9692756 | 0.75 | HIF1A (0.37) | KCNE1KCNQ1HIF1ASLC6A2 | |
| SCHEMBL9370374 | 0.73 | MAOB (0.39) | KCNE1KCNQ1SMN1; SMN2NPSR1CNR1 | |
| SCHEMBL9692444 | 0.70 | HIF1A (0.39) | KCNE1KCNQ1NPSR1HIF1A | |
| SCHEMBL15348113 | 0.70 | CA12 (0.39) | CA12CA1CA9SMN1; SMN2ESR1 | |
| SCHEMBL10513345 | 0.69 | MEN1 (0.32) | HIF1AESR1ESR2MAOB | |
| SCHEMBL8863992 | 0.68 | CA2 (0.47) | KCNE1KCNQ1CNR1SLC6A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL9692351 | 0.68 | SMN1; SMN2 (0.38) | KCNE1KCNQ1CA12CA9SMN1; SMN2 | |
| SCHEMBL6221876 | 0.67 | KMT2A (0.49) | CA12CA1CA9SMN1; SMN2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112855-A | Nootropic Agents | CIBA-GEIGY CORPORATION (US) | 1992-05-12 | — | — | US | disclosed |
| US-4957928-A | NOOTROPIC AGENTS, COGNITION ACTIVATORS | CIBA-GEIGY CORPORATION (US) | 1990-09-18 | — | — | US | disclosed |
| EP-0322361-A2 | Hydrogenated 1-benzooxacycloalkyl pyridine-carboxylic-acid compounds | CIBA-GEIGY AG (CH) | 1989-06-28 | — | — | EP | disclosed |