Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | TSHR | P16473 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9692797 | 0.88 | MAPT (0.43) | RAB9AALDH1A1TSHRLMNAGAA | |
| SCHEMBL9121816 | 0.83 | MAPT (0.44) | RAB9AALDH1A1TSHRLMNAPOLB | |
| SCHEMBL9124271 | 0.81 | RAB9A (0.47) | RAB9AALDH1A1TSHRLMNAPOLB | |
| SCHEMBL9579861 | 0.76 | RAB9A (0.52) | RAB9AALDH1A1TSHRLMNAPOLB | |
| SCHEMBL9692121 | 0.73 | RAB9A (0.57) | RAB9AALDH1A1TSHRLMNAPOLB | |
| SCHEMBL9692380 | 0.72 | ALDH1A1 (0.41) | RAB9AALDH1A1TSHRLMNAPOLB | |
| SCHEMBL9121811 | 0.71 | MAPT (0.45) | RAB9AALDH1A1LMNAGAAKMT2A | |
| SCHEMBL9124267 | 0.69 | MAPT (0.50) | RAB9AALDH1A1TSHRLMNAGAA | |
| SCHEMBL9181076 | 0.68 | KMT2A (0.52) | RAB9AALDH1A1TSHRLMNAKMT2A | |
| SCHEMBL4203340 | 0.67 | L3MBTL1 (0.61) | ALDH1A1TSHRLMNAKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520552-A1 | Derivatives of (hetero) aromatic ethers and thioethers having antihyperlipidemic activity, process for their preparation and pharmaceutical compositions containing them | PIERREL S.p.A. (IT) | 1992-12-30 | — | — | EP | claimed |
| EP-0520552-A1 | Derivatives of (hetero) aromatic ethers and thioethers having antihyperlipidemic activity, process for their preparation and pharmaceutical compositions containing them | PIERREL S.p.A. (IT) | 1992-12-30 | — | — | EP | disclosed |