SCHEMBL9693255

SCHEMBL9693255

Cc1ccc(-c2ccccc2S(=O)(=O)c2ccccc2-c2ccc(C)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAMPT P43490 2/20 0.45
CA12 O43570 2/20 0.45
CA2 P00918 2/20 0.45
CA9 Q16790 2/20 0.45
LMNA P02545 2/20 0.45
MCOLN3 Q8TDD5 1/20 0.45
POLB P06746 2/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
HSD11B1 P28845 1/20 0.43
CA1 P00915 1/20 0.43
GAA P10253 1/20 0.43
AKR1B1 P15121 1/20 0.42
PTGS2 P35354 3/20 0.42
MAPT P10636 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
USP2 O75604 1/20 0.42
ALDH1A1 P00352 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7265178 0.86 PTGS2 (0.50) CA12CA2CA9LMNAMCOLN3
SCHEMBL28175716 0.85 LMNA (0.55) NAMPTCA12CA2CA9LMNA
SCHEMBL8552729 0.84 CA2 (0.53) CA12CA2CA9CA1PTGS2
SCHEMBL5682823 0.84 CA12 (0.42) NAMPTCA12CA2CA9LMNA
SCHEMBL3893623 0.84 POLB (0.46) NAMPTCA12CA2CA9LMNA
SCHEMBL31463127 0.82 AKR1B1 (0.56) NAMPTMEN1KMT2AHSD11B1GAA
SCHEMBL5711493 0.80 PTGS2 (0.52) CA12CA2CA9LMNAMEN1
SCHEMBL9797523 0.79 HSD11B1 (0.57) NAMPTHSD11B1GAAAKR1B1PTGS2
SCHEMBL1271134 0.79 GAA (0.50) CA12CA2CA9LMNAPOLB
SCHEMBL250146 0.79 PTGS2 (0.56) NAMPTHSD11B1GAAAKR1B1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5084530-A Polyether ketone resins for molding materials and extrusion composites AMOCO CORPORATION (US) 1992-01-28 US disclosed
US-5037936-A Bis(acid chloride) terminated polyaryl ether ketone oligomer AMOCO CORPORATION (US) 1991-08-06 US disclosed
US-4975470-A TOUGHNESS, HEAT RESISTANCE, STRESS RESISTANCE, NONCRACKING AMOCO CORPORATION (US) 1990-12-04 US disclosed
US-4968758-A MOLODING MATERIALS WITH EXCELLENT HEAT, SOLVENT, AND STRESS-CRACK RESISTANCE AMOCO CORPORATION (US) 1990-11-06 US disclosed
EP-0195448-B1 PROCESS FOR PREPARING POLY (ARYL ETHER KETONE)S AMOCO CORPORATION (US) 1990-06-20 EP disclosed
EP-0244167-B1 IMPROVED PROCESS FOR PREPARING POLY (ARYL ETHERS) AND POLY (ARYL ETHER KETONES) AMOCO CORPORATION (US) 1990-04-04 EP disclosed
EP-0275295-A4 BLENDS CONTAINING LIQUID CRYSTALLINE POLYESTERS. AMOCO CORP (US) 1990-02-21 EP disclosed
US-4870155-A RANDOM POLYMER OF DIIMIDE-CONTAINING MONOMER, DIHYDRIC PHENOLS AND ACTIVATED DIHALO- OR DINITROBENZOIDS; MELT FABRICABILITY AMOCO CORPORATION (US) 1989-09-26 US disclosed
US-4861915-A Poly (aryl ether ketone) block copolymers AMOCO CORPORATION (US) 1989-08-29 US disclosed
US-4820790-A HEAT RESISTANCE, SOLVENT RESISTANCE AMOCO CORPORATION (US) 1989-04-11 US disclosed
US-4774314-A POLYETHER KETONE POLYMERS AMOCO CORPORATION (US) 1988-09-27 US disclosed
EP-0275295-A1 BLENDS CONTAINING LIQUID CRYSTALLINE POLYESTERS AMOCO CORPORATION (US) 1988-07-27 EP disclosed
US-4748227-A Process for preparing poly(aryl ether)ketones using a sodium carbonate/organic acid salt catalyst AMOCO CORPORATION (US) 1988-05-31 US disclosed
WO-1988000605-A1 BLENDS CONTAINING LIQUID CRYSTALLINE POLYESTERS AMOCO CORPORATION (US) 1988-01-28 WO disclosed
EP-0244167-A1 Improved process for preparing poly (aryl ethers) and poly (aryl ether ketones) AMOCO CORPORATION (US) 1987-11-04 EP disclosed
EP-0213637-A2 Novel polyetherimides AMOCO CORPORATION (US) 1987-03-11 EP disclosed
EP-0211693-A1 Preparation of poly(aryl ether ketones) AMOCO CORPORATION (US) 1987-02-25 EP disclosed
US-4642327-A HIGH TEMPERATURE MOLDING MATERIALS AMOCO CORPORATION (US) 1987-02-10 US disclosed
US-4638044-A Process for preparing poly(aryl ether ketone)s AMOCO CORPORATION (US) 1987-01-20 US disclosed
EP-0195448-A2 Process for preparing poly (aryl ether ketone)s AMOCO CORPORATION (US) 1986-09-24 EP disclosed