SCHEMBL9693595

SCHEMBL9693595

CC(=O)SC[C@@H](Cc1ccccc1C)N=C=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 2/20 0.37
FAP Q12884 1/20 0.37
DPP8 Q6V1X1 1/20 0.37
DPP9 Q86TI2 1/20 0.37
MME P08473 2/20 0.36
ACE P12821 1/20 0.36
CTBP2 P56545 1/20 0.35
PPARG P37231 1/20 0.35
PPARA Q07869 1/20 0.35
MAOB P27338 1/20 0.33
HPGD P15428 2/20 0.33
NOS3 P29474 1/20 0.33
NOS1 P29475 1/20 0.33
NOS2 P35228 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33
DPP7 Q9UHL4 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9321495 1.00 DPP4 (0.37) DPP4FAPDPP8DPP9MME
SCHEMBL8837508 0.82 MME (0.46) MMEACEPPARAHPGDCYP1A2
SCHEMBL9322510 0.76 DPP4 (0.46) DPP4FAPDPP8DPP9MME
SCHEMBL7367328 0.74 PPARG (0.45) MMEACEPPARGPPARAHPGD
SCHEMBL7367331 0.74 PPARG (0.45) MMEACEPPARGPPARAHPGD
SCHEMBL7438291 0.73 PPARA (0.40) MMEACECTBP2PPARGPPARA
SCHEMBL9321498 0.69 CTBP2 (0.35) CTBP2MAOBHPGDALDH1A1
SCHEMBL29308266 0.69 ALDH1A1 (0.46) CTBP2MAOBHPGDALDH1A1TAAR1
SCHEMBL9727438 0.67 PAM (0.41) MMEACEPPARGPPARAHPGD
SCHEMBL6688791 0.66 PPARG (0.49) DPP4CTBP2PPARGPPARAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1992003410-A1 N-(MERCAPTOALKYL)UREAS AND CARBAMATES SCHERING CORPORATION (US) 1992-03-05 WO disclosed