SCHEMBL9694205

SCHEMBL9694205

CC(C)c1ccc(-c2ccc(C(C)CO)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.46
KIF11 P52732 1/20 0.44
ABCB11 O95342 1/20 0.43
PTPN5 P54829 1/20 0.42
TRPA1 O75762 2/20 0.41
HTT P42858 1/20 0.39
TYR P14679 1/20 0.39
GRIA4 P48058 1/20 0.39
ESR1 P03372 1/20 0.38
ESR2 Q92731 1/20 0.38
IDO1 P14902 1/20 0.38
USP5 P45974 1/20 0.37
NPC1 O15118 1/20 0.37
TP53 P04637 1/20 0.37
RAB9A P51151 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10396707 0.93 ABCB11 (0.47) FFAR1ABCB11TRPA1HTTTYR
SCHEMBL9694221 0.93 ABCB11 (0.47) FFAR1ABCB11TRPA1GRIA4ESR1
SCHEMBL10396706 0.93 ABCB11 (0.47) FFAR1ABCB11TRPA1HTTTYR
SCHEMBL2641075 0.85 ABCB11 (0.52) FFAR1ABCB11TRPA1ESR1ESR2
SCHEMBL7409014 0.84 TRPA1 (0.53) FFAR1TRPA1GRIA4
SCHEMBL20377395 0.83 ABCB11 (0.44) ABCB11TRPA1GRIA4ESR1ESR2
Hydrogen Peroxide SCHEMBL9176615 0.80 KIF11 (0.54) FFAR1KIF11PTPN5HTTTYR
Hydrogen Peroxide SCHEMBL9643171 0.80 KIF11 (0.54) FFAR1KIF11PTPN5HTTTYR
SCHEMBL197335 0.80 KIF11 (0.52) FFAR1KIF11PTPN5HTTTYR
SCHEMBL9694465 0.79 ABCB11 (0.42) ABCB11TRPA1GRIA4ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5091592-A Oxidizing 4,4*-diisopropylbiphenyl with molecular oxygen in presence of ammonia or ammonium salt, decomposing using acid catalyst MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1992-02-25 US disclosed