SCHEMBL9694465

SCHEMBL9694465

CC(CO)c1ccc(-c2ccc(C(C)COO)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ABCB11 O95342 1/20 0.42
TRPA1 O75762 3/20 0.36
ESR1 P03372 1/20 0.33
ESR2 Q92731 1/20 0.33
GRIA4 P48058 4/20 0.33
PTGS2 P35354 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8578308 0.94 ABCB11 (0.46) ABCB11TRPA1ESR1ESR2
SCHEMBL9695019 0.86 KIF11 (0.41) ESR1ESR2GRIA4
SCHEMBL3311945 0.85 ESR1 (0.41) ABCB11TRPA1ESR1ESR2
SCHEMBL9694221 0.85 ABCB11 (0.47) ABCB11TRPA1ESR1ESR2GRIA4
SCHEMBL9694205 0.79 FFAR1 (0.46) ABCB11TRPA1ESR1ESR2GRIA4
SCHEMBL2641075 0.78 ABCB11 (0.52) ABCB11TRPA1ESR1ESR2
SCHEMBL13731158 0.78 ACHE (0.48) ESR1ESR2GRIA4
SCHEMBL7409014 0.78 TRPA1 (0.53) TRPA1GRIA4PTGS2
SCHEMBL20377395 0.76 ABCB11 (0.44) ABCB11TRPA1ESR1ESR2GRIA4
SCHEMBL8580830 0.75 TAAR1 (0.52) TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5091592-A Oxidizing 4,4*-diisopropylbiphenyl with molecular oxygen in presence of ammonia or ammonium salt, decomposing using acid catalyst MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1992-02-25 US disclosed