Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.42 |
| ▸ | DHODH | Q02127 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27660488 | 0.69 | KDM4E (0.48) | ALDH1A1HPGDKDM4EHSD17B10TDP1 | |
| SCHEMBL18228978 | 0.67 | ALDH1A1 (0.50) | ALDH1A1HPGDKDM4EHSD17B10TDP1 | |
| SCHEMBL27173843 | 0.67 | KDM4E (0.46) | ALDH1A1HPGDKDM4EHSD17B10TDP1 | |
| SCHEMBL536179 | 0.66 | HTT (0.62) | ALDH1A1HPGDKDM4EHSD17B10TDP1 | |
| SCHEMBL8381593 | 0.66 | CA12 (0.74) | ALDH1A1HPGDKDM4EHSD17B10TDP1 | |
| SCHEMBL7604961 | 0.66 | ACHE (0.50) | KDM4ECA12CA9CA1CA2 | |
| SCHEMBL903067 | 0.66 | ALDH1A1 (0.48) | ALDH1A1HPGDKDM4EHSD17B10TDP1 | |
| SCHEMBL9634001 | 0.65 | HTT (0.61) | ALDH1A1HPGDKDM4EHSD17B10TDP1 | |
| SCHEMBL15517040 | 0.65 | GPR35 (0.57) | ALDH1A1HPGDKDM4EHSD17B10TDP1 | |
| SCHEMBL5842967 | 0.65 | ALDH1A1 (1.00) | ALDH1A1HPGDKDM4EHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0304139-B1 | PROCESS FOR MAKING 5-HYDROXY-3-HYDROXYMETHYL-2-PHENYLFURAN DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-09-11 | — | — | EP | claimed |
| EP-0304139-A1 | Process for making 5-hydroxy-3-hydroxymethyl-2-phenylfuran derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-02-22 | — | — | EP | claimed |
| EP-0266980-B1 | PHARMACEUTICAL COMPOSITIONS, COMPRISING A 2,4-DIPHENYL-1,3-DIOXANE DERIVATIVE AND AN INHIBITOR OF THROMBOXANE A2 SYNTHESIS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-10-28 | — | — | EP | disclosed |
| EP-0304138-B1 | PROCESS FOR MAKING 1,3-DIOXANE DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-03-04 | — | — | EP | disclosed |
| EP-0304139-B1 | PROCESS FOR MAKING 5-HYDROXY-3-HYDROXYMETHYL-2-PHENYLFURAN DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-09-11 | — | — | EP | disclosed |
| US-4925869-A | REACTIVATING ENZYME ACETYLCHOLINESTERASE INHIBITED BY LETHAL DOSE OF SOMAN | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-05-15 | — | — | US | disclosed |
| EP-0347184-A1 | Manufacture of lactol derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-12-20 | — | — | EP | disclosed |
| EP-0304139-A1 | Process for making 5-hydroxy-3-hydroxymethyl-2-phenylfuran derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-02-22 | — | — | EP | disclosed |
| EP-0304138-A1 | Process for making 1,3-dioxane derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-02-22 | — | — | EP | disclosed |
| EP-0266980-A2 | Pharmaceutical compositions, comprising a 2,4-diphenyl-1,3-dioxane derivative and an inhibitor of thromboxane A2 synthesis | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-05-11 | — | — | EP | disclosed |
| EP-0266979-A2 | Therapeutic agents | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-05-11 | — | — | EP | disclosed |