SCHEMBL27660488

SCHEMBL27660488

COc1ccccc1C1=C(C(=O)c2ccccc2)O1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.48
HSD17B10 Q99714 3/20 0.48
HPGD P15428 3/20 0.48
ALDH1A1 P00352 2/20 0.48
TDP1 Q9NUW8 1/20 0.48
RAB9A P51151 3/20 0.46
NPC1 O15118 3/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
ATM Q13315 1/20 0.46
MAPT P10636 6/20 0.45
ALOX15 P16050 1/20 0.45
MAPK1 P28482 1/20 0.45
STK10 O94804 1/20 0.45
SLK Q9H2G2 1/20 0.45
LMNA P02545 4/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2D6 P10635 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27847027 0.76 ATM (0.56) KDM4EHSD17B10HPGDALDH1A1TDP1
SCHEMBL9467809 0.72 CA12 (0.67) KDM4EHSD17B10HPGDALDH1A1TDP1
SCHEMBL27680509 0.72 ALDH1A1 (0.52) HPGDALDH1A1TDP1RAB9ANPC1
SCHEMBL21246919 0.71 PTPRC (0.51) HPGDALDH1A1RAB9AATMMAPT
SCHEMBL29573531 0.71 MAPT (0.64) KDM4EHSD17B10HPGDALDH1A1RAB9A
SCHEMBL50229 0.71 MAPT (0.64) KDM4EHSD17B10HPGDALDH1A1RAB9A
Benzoic Acid SCHEMBL8917895 0.70 RXRA (0.58) KDM4EHSD17B10HPGDALDH1A1TDP1
SCHEMBL16236368 0.70 SLC6A3 (0.65) KDM4EHSD17B10HPGDALDH1A1TDP1
SCHEMBL15125784 0.70 CA12 (0.58) KDM4EHSD17B10HPGDALDH1A1RAB9A
Benzophenone SCHEMBL11416830 0.69 MAPT (0.67) KDM4EHSD17B10HPGDALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1990482-B Flavanonol compounds and their production method and use ZHEJIANG HISUN PHARM CO LTD 2010-12-08 CN claimed
CN-1990482-A Flavanonol compounds and their production method and use ZHEJIANG HISUN NATURELITE PHAR (CN) 2007-07-04 CN claimed
CN-1990482-B Flavanonol compounds and their production method and use ZHEJIANG HISUN PHARM CO LTD 2010-12-08 CN disclosed
CN-1990482-A Flavanonol compounds and their production method and use ZHEJIANG HISUN NATURELITE PHAR (CN) 2007-07-04 CN disclosed