Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | CDC25B | P30305 | 4/20 | 0.48 |
| ▸ | CDC25A | P30304 | 1/20 | 0.48 |
| ▸ | CDC25C | P30307 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3944845 | 0.82 | TSHR (0.69) | TSHRCDC25BCDC25ACDC25CHSD17B10 | |
| SCHEMBL9695883 | 0.81 | ALDH1A1 (0.64) | TSHRCDC25BCDC25ACDC25CHSD17B10 | |
| Hydrochloric Acid SCHEMBL9150908 | 0.81 | TSHR (0.67) | TSHRCDC25BCDC25ACDC25CHSD17B10 | |
| SCHEMBL28061271 | 0.80 | TSHR (0.56) | TSHRCDC25BCDC25ACDC25CHSD17B10 | |
| Hydrochloric Acid SCHEMBL27734207 | 0.72 | CDC25B (0.50) | TSHRCDC25BCDC25ACDC25CHSD17B10 | |
| SCHEMBL3454897 | 0.71 | TSHR (0.67) | TSHRCDC25BCDC25ACDC25CHSD17B10 | |
| SCHEMBL31152339 | 0.71 | TSHR (0.56) | TSHRCDC25BCDC25ACDC25CHSD17B10 | |
| SCHEMBL28904246 | 0.71 | TSHR (0.56) | TSHRCDC25BCDC25ACDC25CHSD17B10 | |
| SCHEMBL9576565 | 0.70 | SCN1A (0.63) | TSHRALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL27424975 | 0.70 | TSHR (0.70) | TSHRCDC25BCDC25ACDC25CHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992002216-A1 | ADVANCED GLYCATION INHIBITORS CONTAINING AMINO-BENZOIC ACIDS AND DERIVATIVES, AND METHODS OF USE | UNIV ROCKEFELLER (US) | 1992-02-20 | — | — | WO | disclosed |