Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | CDC25B | P30305 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27416539 | 0.86 | ALDH1A1 (0.66) | ALDH1A1HSD17B10TSHRCDC25BMAPT | |
| SCHEMBL9695877 | 0.81 | TSHR (0.50) | ALDH1A1HSD17B10TSHRCDC25BSMN1; SMN2 | |
| SCHEMBL7101456 | 0.81 | MMP2 (0.50) | ALDH1A1HSD17B10CDC25BMAPTALOX15 | |
| SCHEMBL2925689 | 0.79 | ALDH1A1 (0.74) | ALDH1A1HSD17B10TSHRCDC25BMAPT | |
| SCHEMBL717606 | 0.79 | ALDH1A1 (0.74) | ALDH1A1HSD17B10TSHRCDC25BMAPT | |
| Ethyl Anthranilate SCHEMBL34474 | 0.79 | ALDH1A1 (1.00) | ALDH1A1HSD17B10TSHRCDC25BMAPT | |
| Ethyl Anthranilate SCHEMBL30055126 | 0.79 | ALDH1A1 (1.00) | ALDH1A1HSD17B10TSHRCDC25BMAPT | |
| SCHEMBL177310 | 0.78 | ALDH1A1 (0.72) | ALDH1A1HSD17B10TSHRCDC25BMAPT | |
| SCHEMBL2894636 | 0.78 | ALDH1A1 (0.72) | ALDH1A1HSD17B10TSHRCDC25BMAPT | |
| Ethyl Anthranilate SCHEMBL7560547 | 0.77 | ALDH1A1 (0.96) | ALDH1A1HSD17B10TSHRCDC25BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992002216-A1 | ADVANCED GLYCATION INHIBITORS CONTAINING AMINO-BENZOIC ACIDS AND DERIVATIVES, AND METHODS OF USE | UNIV ROCKEFELLER (US) | 1992-02-20 | — | — | WO | disclosed |