Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | F13A1 | P00488 | 1/20 | 0.35 |
| ▸ | TGM2 | P21980 | 1/20 | 0.35 |
| ▸ | TGM1 | P22735 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 2/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9694877 | 0.82 | HPGD (0.37) | CA1CA2ACHECHRM2CHRM1 | |
| SCHEMBL9344930 | 0.82 | MAPT (0.40) | CHRM2CHRM1ALOX15MEN1LMNA | |
| SCHEMBL9345469 | 0.82 | ELANE (0.40) | CHRM2CHRM1ALOX15MEN1LMNA | |
| SCHEMBL9696240 | 0.82 | CYP3A4 (0.43) | ALOX15ADRB2ADRA2ADRD2ADRA2C | |
| SCHEMBL9348914 | 0.82 | MAPT (0.40) | CHRM2CHRM1ALOX15MEN1LMNA | |
| SCHEMBL21462592 | 0.81 | MEN1 (0.40) | CA1CA2ACHEABCB1MEN1 | |
| SCHEMBL23055623 | 0.79 | APP (0.42) | ABCB1MEN1LMNAKMT2AKDM4E | |
| SCHEMBL23040691 | 0.79 | APP (0.42) | ABCB1MEN1LMNAKMT2AKDM4E | |
| SCHEMBL9694883 | 0.79 | ALOX15 (0.41) | CHRM2CHRM1ALOX15F13A1TGM2 | |
| Hydrochloric Acid SCHEMBL9346104 | 0.76 | ADRB2 (0.54) | ALOX15MEN1LMNAKMT2AADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5144059-A | CATECHOLAMINE ESTERS | SIMES SOCIETA ITALIANA MEDICINALI E. SINTETICI S.A. (IT) | 1992-09-01 | — | — | US | disclosed |