Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ATP4A | P20648 | 1/20 | 0.33 |
| ▸ | ATP4B | P51164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11444444 | 0.73 | — | — | |
| SCHEMBL24435323 | 0.70 | AOC3 (0.40) | NOS1SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL6468487 | 0.69 | HRH3 (0.37) | HRH3ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL16543301 | 0.69 | NUDT1 (0.46) | SMN1; SMN2HRH3ALDH1A1KMT2AKDM4E | |
| SCHEMBL4721411 | 0.68 | AR (0.38) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL4724793 | 0.68 | AR (0.35) | ALDH1A1MAPTKDM4EAR | |
| SCHEMBL16543303 | 0.68 | NOS2 (0.40) | NOS1HRH3ALDH1A1MEN1KMT2A | |
| SCHEMBL2373929 | 0.67 | NOS1 (0.53) | NOS1SMN1; SMN2ALDH1A1MAPTRAB9A | |
| SCHEMBL5042475 | 0.67 | AR (0.43) | HRH3ALDH1A1MAPTPOLBKDM4E | |
| SCHEMBL5133010 | 0.67 | HRH3 (0.38) | HRH3ALDH1A1MAPTKDM4EAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0481311-A2 | Aminoacid derivatives | MERCK PATENT GmbH (DE) | 1992-04-22 | — | — | EP | disclosed |