Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 12/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9696463 | 0.71 | ALOX5 (0.57) | ALOX5ALOX12FFAR1MTNR1A | |
| Formamide SCHEMBL9695887 | 0.68 | ALOX5 (0.61) | ALOX5FFAR1MTNR1A | |
| SCHEMBL13696683 | 0.66 | ALOX5 (1.00) | ALOX5ALOX12FFAR1 | |
| SCHEMBL9695886 | 0.66 | ALOX5 (1.00) | ALOX5ALOX12FFAR1 | |
| SCHEMBL9741978 | 0.65 | ALOX5 (1.00) | ALOX5ALOX12 | |
| SCHEMBL9696268 | 0.62 | ALOX5 (0.62) | ALOX5MTNR1ANPC1RAB9A | |
| SCHEMBL9490829 | 0.61 | ALOX5 (0.40) | ALOX5ALOX12 | |
| SCHEMBL9729665 | 0.60 | ALOX5 (1.00) | ALOX5ALOX12 | |
| SCHEMBL9694749 | 0.60 | ALOX5 (0.65) | ALOX5MTNR1A | |
| SCHEMBL7791683 | 0.60 | RAB9A (0.47) | ALOX5NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0498770-A1 | Certain benzodioxole, benzodioxane and benzodioxepin derivatives | CIBA-GEIGY AG (CH) | 1992-08-12 | — | — | EP | disclosed |
| US-5120758-A | Treating allergic, inflammatory, cardiovascular, pulmonary, arthritic, cutaneous disorders | CIBA-GEIGY CORPORATION (US) | 1992-06-09 | — | — | US | disclosed |