Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 9/20 | 0.57 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.41 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formamide SCHEMBL9695887 | 0.92 | ALOX5 (0.61) | ALOX5MTNR1AFFAR1AIMP2CA2 | |
| Formamide SCHEMBL9618563 | 0.82 | ALOX5 (0.61) | ALOX5MTNR1AADRB2ADRB1ADRB3 | |
| SCHEMBL9696268 | 0.81 | ALOX5 (0.62) | ALOX5MTNR1AADRB2ADRB1ADRB3 | |
| Formamide SCHEMBL9695948 | 0.79 | MTNR1A (0.60) | ALOX5MTNR1AFFAR1CA2ADRB2 | |
| Formamide SCHEMBL9694812 | 0.78 | ALOX5 (0.61) | ALOX5ADRB2ADRB1ADRB3KDM4E | |
| SCHEMBL9696408 | 0.76 | ALOX5 (0.62) | ALOX5MTNR1AADRB2ADRB1ADRB3 | |
| SCHEMBL9696255 | 0.73 | ALOX5 (0.58) | ALOX5ALOX12ADRB2ADRB1ADRB3 | |
| SCHEMBL9695886 | 0.72 | ALOX5 (1.00) | ALOX5FFAR1ALOX12 | |
| SCHEMBL13696683 | 0.72 | ALOX5 (1.00) | ALOX5FFAR1ALOX12 | |
| SCHEMBL9696458 | 0.71 | ALOX5 (0.49) | ALOX5MTNR1AFFAR1ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0498770-A1 | Certain benzodioxole, benzodioxane and benzodioxepin derivatives | CIBA-GEIGY AG (CH) | 1992-08-12 | — | — | EP | disclosed |
| US-5120758-A | Treating allergic, inflammatory, cardiovascular, pulmonary, arthritic, cutaneous disorders | CIBA-GEIGY CORPORATION (US) | 1992-06-09 | — | — | US | disclosed |