Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 7/20 | 0.61 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | DRD4 | P21917 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formamide SCHEMBL9694812 | 0.96 | ALOX5 (0.61) | ALOX5ADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL9696268 | 0.93 | ALOX5 (0.62) | ALOX5DRD2DRD4DRD3ADRB2 | |
| Formamide SCHEMBL9695887 | 0.90 | ALOX5 (0.61) | ALOX5DRD2DRD4DRD3ADRB2 | |
| SCHEMBL9696255 | 0.89 | ALOX5 (0.58) | ALOX5ADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL9696408 | 0.88 | ALOX5 (0.62) | ALOX5DRD2DRD4DRD3ADRB2 | |
| Formamide SCHEMBL9695948 | 0.86 | MTNR1A (0.60) | ALOX5ADRB2ADRB1ADRB3ALDH1A1 | |
| Formamide SCHEMBL9695907 | 0.82 | ALDH1A1 (0.60) | DRD3ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL9696463 | 0.82 | ALOX5 (0.57) | ALOX5ADRB2ADRB1ADRB3MTNR1A | |
| SCHEMBL9694749 | 0.80 | ALOX5 (0.65) | ALOX5DRD2DRD4DRD3ADRB2 | |
| Formamide SCHEMBL9729642 | 0.79 | ALOX5 (0.61) | ALOX5MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0498770-A1 | Certain benzodioxole, benzodioxane and benzodioxepin derivatives | CIBA-GEIGY AG (CH) | 1992-08-12 | — | — | EP | claimed |
| JP-4338386-A | — | — | None | — | — | JP | disclosed |
| JP-H04338386-A | BENZODIOXOLE, BENZODIOXANE AND BENZODIOXEPIN DERIVATIVES | CIBA GEIGY AG | 1992-11-25 | — | — | JP | disclosed |
| EP-0498770-A1 | Certain benzodioxole, benzodioxane and benzodioxepin derivatives | CIBA-GEIGY AG (CH) | 1992-08-12 | — | — | EP | disclosed |
| US-5120758-A | Treating allergic, inflammatory, cardiovascular, pulmonary, arthritic, cutaneous disorders | CIBA-GEIGY CORPORATION (US) | 1992-06-09 | — | — | US | disclosed |