Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 7/20 | 0.62 |
| ▸ | AKR1C2 | P52895 | 7/20 | 0.62 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | CDC42 | P60953 | 1/20 | 0.62 |
| ▸ | RAC1 | P63000 | 1/20 | 0.62 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.62 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.61 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.58 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15782117 | 0.91 | AKR1C3 (0.56) | AKR1C3AKR1C2PTGS1PTGS2TSHR | |
| SCHEMBL15780716 | 0.90 | AKR1C3 (0.55) | AKR1C3AKR1C2PTGS1PTGS2TSHR | |
| SCHEMBL13828208 | 0.89 | AKR1C3 (0.54) | AKR1C3AKR1C2PTGS1PTGS2TSHR | |
| SCHEMBL9696473 | 0.86 | AKR1C3 (0.60) | AKR1C3AKR1C2PTGS1PTGS2TSHR | |
| SCHEMBL3967988 | 0.86 | ABCB11 (0.67) | AKR1C3AKR1C2PTGS1PTGS2TSHR | |
| SCHEMBL2226074 | 0.84 | L3MBTL1 (0.68) | FFAR1L3MBTL1 | |
| SCHEMBL5858110 | 0.82 | L3MBTL1 (0.59) | FFAR1LMNAL3MBTL1 | |
| SCHEMBL7557544 | 0.82 | AKR1C3 (0.64) | AKR1C3AKR1C2PTGS1PTGS2TSHR | |
| SCHEMBL441219 | 0.82 | AKR1C3 (0.59) | AKR1C3AKR1C2PTGS1PTGS2TSHR | |
| SCHEMBL657936 | 0.80 | GABBR2 (0.50) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180028478-A1 | ANTIVIRAL COMPOSITIONS DIRECTED AGAINST THE NUCLEOPROTEIN OF INFLUENZA VIRUSES | INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (FR) | 2018-02-01 | — | — | US | disclosed |
| US-9783482-B2 | Antiviral compositions directed against the influenza virus nucleoprotein | INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (FR) | 2017-10-10 | — | — | US | disclosed |
| US-20140163107-A1 | ANTIVIRAL COMPOSITIONS DIRECTED AGAINST THE INFLUENZA VIRUS NUCLEOPROTEIN | INSTITUT NATIONAL DE LA RECHERCHE AGRONIMIQUE (FR) | 2014-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180028478-A1 | ANTIVIRAL COMPOSITIONS DIRECTED AGAINST THE NUCLEOPROTEIN OF INFLUENZA VIRUSES | SNRPE, HNRNPA1, ADAR | AKR1C3 4143/4885AKR1C2 4411/4885PTGS1 2901/4885 |
| US-20140163107-A1 | ANTIVIRAL COMPOSITIONS DIRECTED AGAINST THE INFLUENZA VIRUS NUCLEOPROTEIN | SNRPE, HNRNPA1, SNRPF | AKR1C3 4421/4885AKR1C2 4590/4885PTGS1 4453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.