Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8457471 | 0.82 | HIF1A (0.38) | NPC1RAB9AHPGDMAPTALDH1A1 | |
| SCHEMBL9696683 | 0.80 | GRIN1 (0.37) | NPC1RAB9AHPGDMAPTALDH1A1 | |
| SCHEMBL8450128 | 0.76 | TSHR (0.49) | RAB9ATSHRHPGDMAPTALDH1A1 | |
| SCHEMBL4737092 | 0.73 | SLC9A1 (0.34) | NPC1RAB9AHPGDMAPTALDH1A1 | |
| SCHEMBL356141 | 0.73 | TNF (0.47) | ALDH1A1SMN1; SMN2LMNACYP2C9CYP1A2 | |
| SCHEMBL1381878 | 0.72 | SLC9A1 (0.44) | NPC1RAB9ATSHRHPGDMAPT | |
| SCHEMBL9697135 | 0.72 | CYP11B1 (0.57) | NPC1RAB9ATSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL27469643 | 0.70 | TSHR (0.49) | NPC1RAB9ATSHRHPGDMAPT | |
| SCHEMBL16756519 | 0.70 | TSHR (0.52) | NPC1RAB9ATSHRMAPTALDH1A1 | |
| SCHEMBL1828029 | 0.69 | SLC9A1 (0.47) | NPC1RAB9ATSHRHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992006086-A1 | NOVEL 4-PIPERIDINYLCARBONYL DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-04-16 | — | — | WO | disclosed |