Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 4/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL356141 | 0.75 | TNF (0.47) | SMN1; SMN2LMNAALDH1A1CFTRMEN1 | |
| SCHEMBL5757777 | 0.75 | ALOX15 (0.40) | TSHRSMN1; SMN2KDM4EMAPTHSD17B10 | |
| SCHEMBL8450128 | 0.72 | TSHR (0.49) | TSHRSMN1; SMN2KDM4EMAPTHSD17B10 | |
| SCHEMBL4737092 | 0.71 | SLC9A1 (0.34) | SMN1; SMN2KDM4EMAPTHPGDRAB9A | |
| SCHEMBL944723 | 0.71 | TDP1 (0.51) | TSHRSMN1; SMN2MAPTHPGDRAB9A | |
| SCHEMBL1381878 | 0.71 | SLC9A1 (0.44) | TSHRSMN1; SMN2KDM4EMAPTHSD17B10 | |
| SCHEMBL2103982 | 0.71 | POLB (0.39) | TSHRKDM4EMAPTHTTLMNA | |
| SCHEMBL9674199 | 0.70 | CYP11B1 (0.58) | TSHRSMN1; SMN2KDM4EMAPTHSD17B10 | |
| SCHEMBL1650533 | 0.70 | RAB9A (0.48) | TSHRSMN1; SMN2MAPTRAB9AHTT | |
| SCHEMBL945956 | 0.70 | TNF (0.50) | TSHRSMN1; SMN2KDM4EMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1143856-C | Novel substituted N-methyl-N-(4-(4-(1H-benzimidazol-2-yl) [1,4] diazepan-1-yl)-1-(aryl) butyl) benzamides useful for treatment of allergic diseases | ���µ�˹ҩ�﹫˾ | 2004-03-31 | — | — | CN | disclosed |