Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 2/20 | 0.47 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.47 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PDE6D | O43924 | 1/20 | 0.44 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.44 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL944723 | 0.88 | TDP1 (0.51) | TNFGRM2CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL1650533 | 0.86 | RAB9A (0.48) | GRM2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL2541667 | 0.82 | HTT (0.52) | ALDH1A1LMNAKMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL1300677 | 0.82 | MAPT (0.50) | GRM2LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL945956 | 0.80 | TNF (0.50) | TNFALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL7832090 | 0.77 | L3MBTL1 (0.44) | TNFCYP11B1CYP11B2LMNAMEN1 | |
| SCHEMBL1381878 | 0.77 | SLC9A1 (0.44) | SLC9A1ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL2103982 | 0.77 | POLB (0.39) | GRM2SLC9A1ALDH1A1LMNAKMT2A | |
| SCHEMBL11227007 | 0.77 | ALDH1A1 (0.55) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2122189 | 0.76 | ALDH1A1 (0.50) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2477979-B1 | COMPOUNDS FOR ORGANIC LIGHT EMITTING DIODE EMISSIVE LAYERS | NITTO DENKO CORP (JP) | 2016-10-26 | — | — | EP | claimed |
| EP-2477979-A1 | COMPOUNDS FOR ORGANIC LIGHT EMITTING DIODE EMISSIVE LAYERS | Nitto Denko Corporation (JP) | 2012-07-25 | — | — | EP | claimed |
| CN-102596939-A | Compounds for organic light emitting diode emissive layers | NITTO DENKO CORP | 2012-07-18 | — | — | CN | claimed |
| WO-2012012295-A1 | PHOTOTHERAPY DEVICES AND METHODS COMPRISING SUBSTITUTED CARBAZOLE COMPOUNDS | NITTO DENKO CORPORATION (JP) | 2012-01-26 | — | — | WO | claimed |
| US-20120016449-A1 | PHOTOTHERAPY DEVICES AND METHODS COMPRISING SUBSTITUTED CARBAZOLE COMPOUNDS | NITTO DENKO CORPORATION (JP) | 2012-01-19 | — | — | US | claimed |
| WO-2011034967-A1 | COMPOUNDS FOR ORGANIC LIGHT EMITTING DIODE EMISSIVE LAYERS | NITTO DENKO CORPORATION (JP) | 2011-03-24 | — | — | WO | claimed |
| US-20110062386-A1 | COMPOUNDS FOR ORGANIC LIGHT EMITTING DIODE EMISSIVE LAYERS | NITTO DENKO CORPORATION (JP) | 2011-03-17 | — | — | US | claimed |
| US-20080255159-A1 | 8-[3-AMINO-PIPERIDIN-1-YL]-XANTHINES, THE PREPARATION THEREOF AND THEIR USE AS PHARMACEUTICAL COMPOSITIONS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2008-10-16 | — | — | US | claimed |
| US-20040097510-A1 | 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-05-20 | — | — | US | claimed |
| CN-1017801-B | 6- (substituted) hydroxymethyl penicillanic acids or 1, 1-dioxides and derivatives thereof | PFIZER (US) | 1992-08-12 | — | — | CN | claimed |
| CN-1017802-B | METHOD FOR PREPARING 6-(SUBSTD.) HYDROXYMETHYL-PENICILLANIC ACIDS OR 1,1-DIOXIDE AND DERIVS THEREOF | PFIZER (US) | 1992-08-12 | — | — | CN | claimed |
| CN-1015462-B | METHOD FOR PREPARING 6-(SUBSTD.) METHYLENEPENICILLANIC ACIDS OR 1,1-DIOXIDE AND DERIVATIVES THEREOF | PFIZER (US) | 1992-02-12 | — | — | CN | claimed |
| EP-0150984-B1 | 6-(SUBSTITUTED) METHYLENEPENICILLANIC AND 6-(SUBSTITUTED) HYDROXYMETHYLPENICILLANIC ACIDS AND DERIVATIVES THEREOF | PFIZER INC. (US) | 1991-09-11 | — | — | EP | claimed |
| CN-1046905-A | 6-(replacement) methylene radical penam acids; The method for making of 6-(replacement) methylol penicillin alkanoic acid class and derivative thereof | PFIZER (US) | 1990-11-14 | — | — | CN | claimed |
| CN-1045788-A | 6-(replacement) methylene radical penam acids; The method for making of 6-(replacement) methylol penicillin alkanoic acid class and derivative thereof | PFIZER (US) | 1990-10-03 | — | — | CN | claimed |
| CN-1045787-A | The method for making of 6-(replacement) methylene radical penam acids, 6-(replacement) methylol penam acids and derivative thereof | PFIZER (US) | 1990-10-03 | — | — | CN | claimed |
| CN-1045789-A | 6-(replacement) methylene radical penam acids; The method for making of 6-(replacement) methylol penam acids and derivative thereof | PFIZER (US) | 1990-10-03 | — | — | CN | claimed |
| US-4758568-A | Quinoline therapeutic agents | PFIZER INC. (US) | 1988-07-19 | — | — | US | claimed |
| CN-85101572-A | Process for producing 6- (substituted) methylenepenicillanic acids, 6- (substituted) hydroxymethylpenicillanic acids and derivatives thereof | — | 1986-10-29 | — | — | CN | claimed |
| EP-0150984-A2 | 6-(Substituted) methylenepenicillanic and 6-(substituted) hydroxymethylpenicillanic acids and derivatives thereof | PFIZER INC. (US) | 1985-08-07 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255159-A1 | 8-[3-AMINO-PIPERIDIN-1-YL]-XANTHINES, THE PREPARATION THEREOF AND THEIR USE AS PHARMACEUTICAL COMPOSITIONS | DPP8, DPP4, DPP3 | TNF 3583/4885GRM2 1319/4885CYP11B1 1403/4885 |
| US-20120016449-A1 | PHOTOTHERAPY DEVICES AND METHODS COMPRISING SUBSTITUTED CARBAZOLE COMPOUNDS | TYR, PPOX, CRY1 | TNF 2114/4885GRM2 2830/4885CYP11B1 39/4885 |
| US-20110062386-A1 | COMPOUNDS FOR ORGANIC LIGHT EMITTING DIODE EMISSIVE LAYERS | ALOX12, ALOX15B, ALOX15 | TNF 3362/4885GRM2 1468/4885CYP11B1 78/4885 |
| US-20040097510-A1 | 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions | DPP8, DPP4, DPP3 | TNF 3802/4885GRM2 1546/4885CYP11B1 848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.