Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.41 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL10802671 | 0.95 | GRIN2B (0.41) | SLC6A9SSTR5GRIN2B | |
| Oxalic Acid SCHEMBL9538518 | 0.95 | GRIN2B (0.41) | SLC6A9SSTR5GRIN2B | |
| Oxalic Acid SCHEMBL9538513 | 0.95 | GRIN2B (0.41) | SLC6A9SSTR5GRIN2B | |
| SCHEMBL9536807 | 0.90 | SSTR5 (0.50) | SSTR5NR4A2KCNH2HTR1AHTR2C | |
| SCHEMBL9537190 | 0.87 | PRMT3 (0.44) | SLC6A9SSTR5GRM2KCNH2CYP2D6 | |
| SCHEMBL9535415 | 0.86 | SLC6A9 (0.55) | SLC6A9HTR3EHTR3BHTR1AHTR2C | |
| SCHEMBL9537238 | 0.86 | KCNH2 (0.43) | SLC6A9SSTR5NR4A2KCNH2CYP2D6 | |
| SCHEMBL9536547 | 0.84 | SSTR5 (0.52) | SSTR5ACHEBACE1HTR3EHTR3B | |
| SCHEMBL10551207 | 0.83 | SSTR5 (0.58) | SSTR5ACHEBACE1NR4A2KCNH2 | |
| SCHEMBL9538238 | 0.82 | MEN1 (0.49) | SSTR5GRM2GRIN2BCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0151826-B1 | 4-[(Bicyclic heterocyclyl)-methyl and -hetero]-piperidines | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-03-31 | — | — | EP | claimed |