Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.48 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9490990 | 0.93 | NPSR1 (0.53) | KMT2AMEN1RAB9ANPSR1MMP2 | |
| SCHEMBL9699725 | 0.91 | NPSR1 (0.49) | KMT2AMEN1RAB9ANPSR1MMP2 | |
| SCHEMBL10458998 | 0.91 | NPSR1 (0.49) | KMT2AMEN1RAB9ANPSR1MMP2 | |
| SCHEMBL10458996 | 0.90 | MMP2 (0.52) | KMT2AMEN1RAB9ANPSR1MMP2 | |
| SCHEMBL9490445 | 0.86 | MMP2 (0.54) | KMT2AMEN1MMP2KCNN4KCNA3 | |
| SCHEMBL10461110 | 0.84 | NPSR1 (0.51) | KMT2AMEN1RAB9ANPSR1ALDH1A1 | |
| SCHEMBL9491040 | 0.79 | MAPT (0.53) | KMT2AMEN1RAB9ANPSR1ALDH1A1 | |
| SCHEMBL9490572 | 0.77 | MMP2 (0.55) | KMT2AMEN1MMP2KCNN4KCNA3 | |
| SCHEMBL9489398 | 0.76 | MMP2 (0.56) | MMP2ALDH1A1PKMMAPTPOLB | |
| Acetic Acid SCHEMBL10461101 | 0.75 | MMP2 (0.53) | KMT2AMEN1MMP2KCNN4KCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992005160-A1 | 4-ARYLSULFONYL-3,4-DIHYDRO-2(1H)-QUINOXALINONE-1-ALKANOIC ACIDS, ESTERS, AND SALTS | SARGES REINHARD (US) | 1992-04-02 | — | — | WO | disclosed |
| US-4940708-A | 4-arylsulfonyl-3,4-dihydro-2(1H)-quinoxalinone-1-alkanoic acids, esters, and salts | PFIZER INC. (US) | 1990-07-10 | — | — | US | disclosed |