Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.56 |
| ▸ | CTSG | P08311 | 1/20 | 0.47 |
| ▸ | CMA1 | P23946 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9490572 | 0.88 | MMP2 (0.55) | MMP2ALDH1A1PKMPOLBCYP3A4 | |
| SCHEMBL9490445 | 0.87 | MMP2 (0.54) | MMP2CTSGCMA1ALDH1A1LMNA | |
| SCHEMBL10458996 | 0.87 | MMP2 (0.52) | MMP2CTSGCMA1NPC1ALDH1A1 | |
| SCHEMBL9490432 | 0.85 | MMP2 (0.54) | MMP2CTSGCMA1ALDH1A1PKM | |
| SCHEMBL9490689 | 0.85 | MMP2 (0.54) | MMP2CTSGCMA1ALDH1A1PDPK1 | |
| SCHEMBL9490990 | 0.78 | NPSR1 (0.53) | MMP2ALDH1A1HSD17B10LMNAPKM | |
| SCHEMBL9490595 | 0.78 | CTSG (0.44) | MMP2CTSGCMA1ALDH1A1HSD17B10 | |
| SCHEMBL9697221 | 0.76 | KMT2A (0.53) | MMP2ALDH1A1LMNAPKMPOLB | |
| Acetic Acid SCHEMBL10461101 | 0.76 | MMP2 (0.53) | MMP2ALDH1A1HSD17B10PKMPOLB | |
| SCHEMBL10458998 | 0.75 | NPSR1 (0.49) | MMP2ALDH1A1LMNAPKMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0266102-B1 | QUINOXALINONE DERIVATIVES | PFIZER INC. (US) | 1993-03-17 | — | — | EP | disclosed |
| US-4940708-A | 4-arylsulfonyl-3,4-dihydro-2(1H)-quinoxalinone-1-alkanoic acids, esters, and salts | PFIZER INC. (US) | 1990-07-10 | — | — | US | disclosed |