Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10458998 | 0.86 | NPSR1 (0.49) | MAPTHTTUSP2LMNAGAA | |
| SCHEMBL10459002 | 0.86 | L3MBTL1 (0.50) | MAPTUSP2LMNAGAATSHR | |
| SCHEMBL10461110 | 0.83 | NPSR1 (0.51) | MAPTHTTUSP2LMNAGAA | |
| SCHEMBL9490990 | 0.81 | NPSR1 (0.53) | MAPTHTTUSP2LMNAGAA | |
| SCHEMBL9697221 | 0.79 | KMT2A (0.53) | MAPTLMNAGAASMN1; SMN2NPSR1 | |
| SCHEMBL9699725 | 0.78 | NPSR1 (0.49) | MAPTLMNAGAANPSR1TSHR | |
| SCHEMBL10458996 | 0.77 | MMP2 (0.52) | MAPTLMNAGAANPSR1TSHR | |
| SCHEMBL9490689 | 0.70 | MMP2 (0.54) | MAPTTSHRALDH1A1MEN1KMT2A | |
| SCHEMBL9490595 | 0.70 | CTSG (0.44) | MAPTHTTLMNASMN1; SMN2TSHR | |
| SCHEMBL12571561 | 0.69 | HTT (0.62) | MAPTHTTUSP2LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0266102-B1 | QUINOXALINONE DERIVATIVES | PFIZER INC. (US) | 1993-03-17 | — | — | EP | disclosed |
| US-4940708-A | 4-arylsulfonyl-3,4-dihydro-2(1H)-quinoxalinone-1-alkanoic acids, esters, and salts | PFIZER INC. (US) | 1990-07-10 | — | — | US | disclosed |