SCHEMBL9697299

SCHEMBL9697299

CC(C)c1ccccc1O[Si](C)(C)C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RX3 P56373 1/20 0.44
P2RX2 Q9UBL9 1/20 0.44
NISCH Q9Y2I1 2/20 0.42
ADRA2A P08913 1/20 0.42
ADRA2B P18089 1/20 0.42
ADRA2C P18825 1/20 0.42
GABRA1 P14867 2/20 0.41
GABRB2 P47870 2/20 0.41
CYP1A2 P05177 3/20 0.39
KMT2A Q03164 3/20 0.39
CYP3A4 P08684 2/20 0.39
MEN1 O00255 2/20 0.39
CYP2C19 P33261 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
CYP2C9 P11712 1/20 0.39
RECQL P46063 1/20 0.39
LMNA P02545 3/20 0.38
ALDH1A1 P00352 1/20 0.38
SLC6A2 P23975 3/20 0.38
TSHR P16473 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16098475 0.83 CYP2D6 (0.38) P2RX3P2RX2ADRA2AADRA2CCYP1A2
SCHEMBL15242458 0.80 P2RX3 (0.43) P2RX3P2RX2NISCHADRA2AADRA2B
SCHEMBL3292456 0.79 ALDH1A1 (0.34) CYP1A2CYP2C19CYP2C9LMNAALDH1A1
SCHEMBL6703730 0.78 CA1 (0.45) ADRA2BKMT2AMEN1L3MBTL1LMNA
SCHEMBL28480728 0.78 GPR84 (0.37) NISCHKMT2AMEN1L3MBTL1LMNA
SCHEMBL11044064 0.77 GABRA1 (0.39) GABRA1GABRB2CYP1A2CYP3A4LMNA
SCHEMBL4575432 0.77 P2RX3 (0.58) P2RX3P2RX2NISCHADRA2AADRA2B
SCHEMBL141647 0.77 CA1 (0.60) P2RX3P2RX2ADRA2BGABRA1GABRB2
SCHEMBL31257131 0.77 CA1 (0.60) P2RX3P2RX2ADRA2BGABRA1GABRB2
SCHEMBL29959656 0.77 P2RX3 (0.58) P2RX3P2RX2NISCHADRA2AADRA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5080971-A Durable, weatherproof, wear and corrosion resistant TDK CORPORATION (JP) 1992-01-14 US disclosed
US-5069967-A Durability, thin metal film. plasma polymerized film, fluoropo lymer film TDK CORPORATION (JP) 1991-12-03 US disclosed
US-4988573-A MAGNETIC RECORDING MEDIA, PLASMA POLYMERIZED FILM ON A SURFACE SUCH AS A TAPE OR DISK TDK CORPORATION (JP) 1991-01-29 US disclosed