Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | WDR5 | P61964 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3830527 | 0.76 | ALDH1A1 (0.43) | TSHRRAB9AL3MBTL1WDR5LDHA | |
| SCHEMBL30405639 | 0.76 | RAB9A (0.41) | TSHRRAB9AL3MBTL1NOTUMALDH1A1 | |
| SCHEMBL5635938 | 0.75 | KDM4E (0.44) | HPGDALDH1A1HSD17B10KDM4E | |
| SCHEMBL30705807 | 0.74 | FABP4 (0.45) | TSHRRAB9AL3MBTL1NOTUM | |
| SCHEMBL21055089 | 0.74 | TSHR (0.40) | TSHRRAB9AL3MBTL1NOTUMHPGD | |
| SCHEMBL15971447 | 0.74 | NOTUM (0.41) | TSHRRAB9AL3MBTL1NOTUMALDH1A1 | |
| SCHEMBL31056496 | 0.74 | NR4A1 (0.46) | TSHRRAB9AL3MBTL1NOTUMNR4A1 | |
| SCHEMBL4048895 | 0.74 | NOTUM (0.42) | TSHRRAB9AL3MBTL1NOTUMHPGD | |
| Hydrochloric Acid SCHEMBL31056543 | 0.73 | NR4A1 (0.44) | TSHRRAB9AL3MBTL1LDHANOTUM | |
| SCHEMBL931955 | 0.72 | TSHR (0.69) | TSHRRAB9AL3MBTL1NOTUMHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992002219-A1 | TETRACYCLIC AMINES USEFUL AS CEREBROVASCULAR AGENTS | WARNER-LAMBERT COMPANY (US) | 1992-02-20 | — | — | WO | claimed |