Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8068895 | 0.84 | MAOA (0.35) | HSD17B3CA1CA2PARP1MAOA | |
| SCHEMBL7529245 | 0.71 | CA1 (0.35) | HSD17B3CA1CA2PARP1MAOA | |
| SCHEMBL258234 | 0.71 | PARP1 (0.36) | CA1CA2PARP1MAOB | |
| SCHEMBL31520302 | 0.71 | PARP1 (0.36) | CA1CA2PARP1MAOB | |
| SCHEMBL4734678 | 0.70 | MAOA (0.33) | CA1CA2PARP1MAOAMAOB | |
| SCHEMBL11741518 | 0.70 | HSD11B1 (0.36) | HSD17B3MAOAMAOBHDAC9HSD11B1 | |
| SCHEMBL2288761 | 0.70 | PARP1 (0.39) | CA1CA2PARP1MAOB | |
| SCHEMBL28924809 | 0.69 | HSD17B3 (0.35) | HSD17B3CA1CA2PARP1 | |
| SCHEMBL7878420 | 0.69 | SRC (0.32) | CA1CA2PARP1 | |
| SCHEMBL23781284 | 0.68 | PARP1 (0.34) | CA1CA2PARP1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0463246-A1 | Process for preparing aromatic copolyester | Showa Shell Sekiyu Kabushiki Kaisha (JP) | 1992-01-02 | — | — | EP | disclosed |
| US-5045626-A | 2,7-Naphthalenedicarboxylate | SHOWA SHELL SEKIYU KABUSHIKI KAISHA (JP) | 1991-09-03 | — | — | US | disclosed |