Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1B | O75688 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11393084 | 1.00 | PPM1B (0.61) | PPM1BALDH1A1TDP1L3MBTL1KDM4E | |
| SCHEMBL6778458 | 1.00 | PPM1B (0.61) | PPM1BALDH1A1TDP1L3MBTL1KDM4E | |
| SCHEMBL13897079 | 1.00 | PPM1B (0.61) | PPM1BALDH1A1TDP1L3MBTL1KDM4E | |
| SCHEMBL13480836 | 1.00 | PPM1B (0.61) | PPM1BALDH1A1TDP1L3MBTL1KDM4E | |
| SCHEMBL1005051 | 1.00 | PPM1B (0.61) | PPM1BALDH1A1TDP1L3MBTL1KDM4E | |
| SCHEMBL13002242 | 0.88 | PPM1B (0.52) | PPM1BALDH1A1TDP1L3MBTL1KDM4E | |
| SCHEMBL16675540 | 0.88 | PPM1B (0.56) | PPM1BALDH1A1TDP1L3MBTL1KDM4E | |
| SCHEMBL9880145 | 0.88 | PPM1B (0.56) | PPM1BALDH1A1TDP1L3MBTL1KDM4E | |
| SCHEMBL819846 | 0.88 | PPM1B (0.56) | PPM1BALDH1A1TDP1L3MBTL1KDM4E | |
| SCHEMBL9058158 | 0.88 | PPM1B (0.52) | PPM1BALDH1A1TDP1L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084539-A | Ring opening polymerization of cyclic olefins useful in water treatment | CIBA-GEIGY CORPORATION (US) | 1992-01-28 | — | — | US | disclosed |