SCHEMBL6778458

SCHEMBL6778458

O=C(O)[C@@H]1[C@H](C(=O)O)[C@@H]2C=C[C@H]1O2

nearest known ligand 0.61

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PPM1B O75688 3/20 0.61
ALDH1A1 P00352 7/20 0.47
TDP1 Q9NUW8 3/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
KDM4E B2RXH2 2/20 0.47
TP53 P04637 1/20 0.47
GAA P10253 1/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
HSD17B10 Q99714 1/20 0.47
LMNA P02545 1/20 0.45
MAPT P10636 1/20 0.44
POLB P06746 2/20 0.43
CTDSP1 Q9GZU7 1/20 0.43
APEX1 P27695 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11393084 1.00 PPM1B (0.61) PPM1BALDH1A1TDP1L3MBTL1KDM4E
SCHEMBL13897079 1.00 PPM1B (0.61) PPM1BALDH1A1TDP1L3MBTL1KDM4E
SCHEMBL9697481 1.00 PPM1B (0.61) PPM1BALDH1A1TDP1L3MBTL1KDM4E
SCHEMBL13480836 1.00 PPM1B (0.61) PPM1BALDH1A1TDP1L3MBTL1KDM4E
SCHEMBL1005051 1.00 PPM1B (0.61) PPM1BALDH1A1TDP1L3MBTL1KDM4E
SCHEMBL13002242 0.88 PPM1B (0.52) PPM1BALDH1A1TDP1L3MBTL1KDM4E
SCHEMBL16675540 0.88 PPM1B (0.56) PPM1BALDH1A1TDP1L3MBTL1KDM4E
SCHEMBL9880145 0.88 PPM1B (0.56) PPM1BALDH1A1TDP1L3MBTL1KDM4E
SCHEMBL819846 0.88 PPM1B (0.56) PPM1BALDH1A1TDP1L3MBTL1KDM4E
SCHEMBL9058158 0.88 PPM1B (0.52) PPM1BALDH1A1TDP1L3MBTL1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116606619-B Preparation method of single-component epoxy resin adhesive electronic pouring sealant 山东凯恩新材料科技有限公司 2023-09-26 CN disclosed
CN-116606619-A Preparation method of single-component epoxy resin adhesive electronic pouring sealant 山东凯恩新材料科技有限公司 2023-08-18 CN disclosed
US-6677464-B2 REACTING ALPHA, BETA-UNSATURATED CARBOXYLIC ACID WITH FURAN DERIVATIVE IN PRESENCE OF LEWIS ACID KURARAY CO., LTD. (JP) 2004-01-13 US disclosed
US-20030187282-A1 PROCESS FOR PREPARATION OF 7-OXABICYCLO[2.2.1]HEPT-5-ENE-2-CARBOXYLIC ACID DERIVATIVES KURARAY CO., LTD. (JP) 2003-10-02 US disclosed
EP-1319662-A1 PROCESS FOR PREPARATION OF 7-OXABICYCLO 2.2.1]HEPT-5-ENE-2-CARBOXYLIC ACID DERIVATIVES Kuraray Co., Ltd. (JP) 2003-06-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030187282-A1 PROCESS FOR PREPARATION OF 7-OXABICYCLO[2.2.1]HEPT-5-ENE-2-CARBOXYLIC ACID DERIVATIVES ALOX5, ALOX15B, ALOX15 PPM1B 2131/4885ALDH1A1 39/4885TDP1 4857/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.