Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 6/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 5/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9696668 | 1.00 | DHFR (0.33) | DHFRALDH1A1TSHRCHRM2CHRM4 | |
| SCHEMBL9696729 | 0.86 | TP53 (0.34) | ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL7272818 | 0.86 | TP53 (0.34) | ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL8882126 | 0.86 | TP53 (0.34) | ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL7276157 | 0.86 | TP53 (0.34) | ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL8170961 | 0.86 | ALDH1A1 (0.38) | ALDH1A1TSHRL3MBTL1LMNAADORA3 | |
| SCHEMBL2809476 | 0.86 | ALDH1A1 (0.38) | ALDH1A1TSHRL3MBTL1LMNAADORA3 | |
| SCHEMBL11930533 | 0.86 | LMNA (0.36) | ALDH1A1TSHRL3MBTL1LMNAADORA3 | |
| SCHEMBL14256287 | 0.85 | HSD11B1 (0.40) | ALDH1A1TSHRL3MBTL1LMNA | |
| SCHEMBL12327949 | 0.83 | MAPK1 (0.33) | ALDH1A1TSHRLMNAADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992002521-A1 | 1-AZABICYCLO[3.2.0]HEPT-2-ENE-2-CARBOXYLIC ACID COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-02-20 | — | — | WO | disclosed |