Known targets — ChEMBL curated mechanism
ACEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2BTKCACNA1CCACNA1DCACNA1FCACNA1SCCR5CPT1BCPT2DPP4DRD1DRD2EGFRERBB2ERBB4HRH1HRH3HTR1AHTR2AHTR2BHTR2CHTR4JAK1JAK2JAK3MPLMTORPPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PPARGSLC6A2SLC6A3SLC6A4SMOTYK2pol
The experimentally established mechanism targets of Maleic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Maleic Acid SCHEMBL8867962 | 1.00 | — | — | |
| SCHEMBL8866960 | 0.88 | — | — | |
| SCHEMBL8867835 | 0.88 | — | — | |
| Fumaric Acid SCHEMBL8867969 | 0.88 | — | — | |
| Maleic Acid SCHEMBL9698742 | 0.88 | — | — | |
| Maleic Acid SCHEMBL8867958 | 0.88 | — | — | |
| Fumaric Acid SCHEMBL8866982 | 0.86 | — | — | |
| Fumaric Acid SCHEMBL8866997 | 0.86 | — | — | |
| Fumaric Acid SCHEMBL8866989 | 0.86 | — | — | |
| Fumaric Acid SCHEMBL8867142 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0491562-A1 | Novel spirofurane derivatives | FISONS CORPORATION (US) | 1992-06-24 | — | — | EP | disclosed |