Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6450630 | 0.86 | MTNR1A (0.50) | MEN1KMT2ARAB9ALMNA | |
| SCHEMBL9699480 | 0.84 | HTR2A (0.54) | HTR6HDAC6HDAC10 | |
| SCHEMBL27846733 | 0.76 | HTR6 (0.40) | HTR6KCNA5KDM4EKCNH2MEN1 | |
| SCHEMBL12368655 | 0.74 | MAPT (0.62) | KDM4EMEN1KMT2ALMNAMAPT | |
| SCHEMBL21614239 | 0.73 | KDM4E (0.60) | KDM4EMEN1KMT2ARAB9AHDAC6 | |
| SCHEMBL12017348 | 0.73 | MEN1 (0.46) | HTR6KDM4EMEN1KMT2ARAB9A | |
| SCHEMBL7675381 | 0.70 | HTR6 (0.55) | HTR6MEN1KMT2A | |
| SCHEMBL2535085 | 0.68 | ALDH1A1 (0.41) | KDM4EMEN1KMT2ATP53CDK2 | |
| SCHEMBL2535097 | 0.68 | ALDH1A1 (0.41) | HTR6KDM4EMEN1KMT2ATP53 | |
| SCHEMBL29169605 | 0.67 | L3MBTL1 (0.58) | HTR6MEN1KMT2ARAB9AHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004075847-A2 | METHODS AND COMPOUNDS FOR THE TREATMENT OF Aß ASSOCIATED DISEASES, DISORDERS, AND CONDITIONS | MESSAGE PHARMACEUTICALS, INC. (US) | 2004-09-10 | — | — | WO | disclosed |