Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | TP53 | P04637 | 4/20 | 0.56 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.56 |
| ▸ | ENPP2 | Q13822 | 8/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9699244 | 0.88 | ENPP2 (0.64) | MAPTTP53TBXA2RENPP2LMNA | |
| SCHEMBL9682037 | 0.85 | RXFP1 (0.44) | MAPTTP53TBXA2RENPP2LMNA | |
| SCHEMBL9681424 | 0.85 | TBXA2R (0.59) | MAPTTP53TBXA2RALDH1A1 | |
| SCHEMBL9700273 | 0.78 | TBXA2R (0.77) | MAPTTP53TBXA2RENPP2LMNA | |
| SCHEMBL9581584 | 0.78 | TBXA2R (0.64) | TBXA2R | |
| SCHEMBL18012398 | 0.76 | LMNA (0.73) | MAPTTP53ENPP2LMNAMEN1 | |
| SCHEMBL30100280 | 0.76 | LMNA (0.73) | MAPTTP53ENPP2LMNAMEN1 | |
| SCHEMBL9699186 | 0.73 | TP53 (0.54) | MAPTTP53TBXA2RLMNAMEN1 | |
| SCHEMBL19771389 | 0.73 | ENPP2 (0.82) | MAPTTP53ENPP2LMNAMEN1 | |
| SCHEMBL19771388 | 0.73 | LMNA (0.82) | MAPTTP53ENPP2LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5124336-A | Cardiovascular disorders | LABORATOIRES UPSA (FR) | 1992-06-23 | — | — | US | disclosed |