Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9702147 | 0.93 | CA1 (0.36) | KMT2ASMN1; SMN2ALDH1A1MEN1LMNA | |
| SCHEMBL9702143 | 0.74 | MAOB (0.32) | KDM4E | |
| SCHEMBL9701430 | 0.70 | CA1 (0.33) | SMN1; SMN2LMNA | |
| SCHEMBL9701113 | 0.66 | MAOB (0.31) | — | |
| SCHEMBL9701219 | 0.64 | AKR1B1 (0.37) | AKR1B1ALDH1A1MAPK1L3MBTL1HRH4 | |
| SCHEMBL9700201 | 0.64 | DRD1 (0.33) | SMN1; SMN2KDM4ELMNAPOLBMAPK1 | |
| SCHEMBL27453650 | 0.64 | PNMT (0.41) | AKR1B1ALDH1A1KDM4ELMNAPOLB | |
| SCHEMBL9700197 | 0.63 | MAOB (0.32) | KMT2ASMN1; SMN2ALDH1A1KDM4EMEN1 | |
| SCHEMBL13993102 | 0.59 | ALDH1A1 (0.38) | AKR1B1KMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL17293067 | 0.55 | AHR (0.44) | AKR1B1ALDH1A1MAPK1L3MBTL1HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992013860-A1 | NEW 4,5,6,7-TETRAHYDRO-IMIDAZO-[4,5,lJK][1,4]-BENZODIAZEPINE-2-(1H)-THIONES, A METHOD OF PREPARING THEM AS WELL AS DRUGS CONTAINING THEM, AND INTERMEDIATES FOR THE PREPARATION OF THESE COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1992-08-20 | — | — | WO | disclosed |